DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10748 and SPCC306.08c

DIOPT Version :9

Sequence 1:	NP_648615.1	Gene:	CG10748 / 39469	FlyBaseID:	FBgn0036327	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001342887.1	Gene:	SPCC306.08c / 2538766	PomBaseID:	SPCC306.08c	Length:	341	Species:	Schizosaccharomyces pombe

Alignment Length:	331	Identity:	149/331 - (45%)
Similarity:	203/331 - (61%)	Gaps:	6/331 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TSLKSLAKPATWGVVVRTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMKGIATDLSHI 69
            |.|||:|..:......|..||||:|||||||||||:||:....:.||||.|:....|:|.|:.||
pombe    11 TPLKSIAPRSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGAPGVAADIGHI 75

  Fly    70 SQTGKVIGFT-GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRA 133
            :.|..|:|:. .:|.||.|::|||||::.||:||.|||.||.|.|.|.::...:|.|.....|.|
pombe    76 NTTSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETCPEA 140

  Fly   134 HLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGH 198
            ....:|||||..||...:.|...|....:.|||:||||.||:.:|.....|...:.::|||:|||
pombe   141 KYLVVTNPVNSTVPIFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNGKAELLHIPVVGGH 205

  Fly   199 AGITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRG 263
            :|.||:||:||.......:.::.  |.||||..|.|||.||||.||||||||||||...:|:||.
pombe   206 SGATIVPLLSQGGVELTGEKRDA--LIHRIQFGGDEVVKAKAGAGSATLSMAYAGARMASSVLRA 268

  Fly   264 IAGQDGLIECAFVASKL---TDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEKLLPILRQNA 325
            :||:.|:.||.||.|.|   ....||||.:.|||||:....|:.:::|||:..|:..|..|:::.
pombe   269 LAGESGVEECTFVESPLYKDQGIDFFASRVTLGKDGVDTIHPVGKINDYEESLLKVALGELKKSI 333

  Fly   326 DEGVNF 331
            .:|..|
pombe   334 TKGEQF 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_euk_gproteo	36..333	CDD:130833	132/300 (44%)
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	132/300 (44%)
SPCC306.08c	NP_001342887.1	MDH_glyoxysomal_mitochondrial	29..340	CDD:133422	143/313 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	143	1.000	Domainoid score	I1165
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I575
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	1	1.000	-	-		otm47343
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1106
TreeFam	1	0.960	-	-
	9	8.920