Protein Alignment CG10748 and mdh-2

DIOPT Version :9

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_498457.1
• Gene: mdh-2 / 175936
• WormBaseID: WBGene00003162
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 334
• Identity: 161/334 - (48%)
• Similarity: 223/334 - (66%)
• Gaps: 6/334 - (1%)

  Fly     5 TSLKSLAKPATWGVVVR----TLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMKGIATD 65
            |.:::.|......|.||    ..|||::||.|||||||.|||::.|.:..|||:|:....|:|.|
 Worm     7 TLVQAAANSGLRAVSVRHSSQAPKVALLGAAGGIGQPLGLLLKQDPLVAHLALYDVVNTPGVAAD 71

  Fly    66 LSHISQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNAS 130
            ||||....||...||.|||.:||..|||:|:.||:||.|||.||.|...|..:...:|..|:.||
 Worm    72 LSHIDSNAKVTAHTGPKELYAAVENADVIVIPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKAS 136

  Fly   131 PRAHLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVI 195
            |:|.:|.||||||..||.|:|||...|.:|.:|:||:||||||||:.|:.:..........:||:
 Worm   137 PKALIAIITNPVNSTVPIASEVLKKAGVYDPKRVFGVTTLDVVRSQAFVSELKGHDASKTVVPVV 201

  Fly   196 GGHAGITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSL 260
            ||||||||:||:||.:|..:...:||..||.|||:|||||||||||.||||||||.|||.|.|:|
 Worm   202 GGHAGITIIPLLSQVKPSTKFSEEEISKLTPRIQDAGTEVVNAKAGAGSATLSMALAGARFANAL 266

  Fly   261 LRGIAGQDGLIECAFVAS-KLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEKLLPILRQN 324
            :|||.|:.. ::||:||| .:....:|::|:|||.:|:::.:.:.::|.||::.::..:|.|.:|
 Worm   267 VRGIKGEKN-VQCAYVASDAVKGVEYFSTPVELGPNGVEKILGVGKVSAYEQKLIDASVPELNKN 330

  Fly   325 ADEGVNFAK 333
            ..:||.|.|
 Worm   331 IAKGVAFVK 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_euk_gproteo	36..333	CDD:130833	146/297 (49%)
		MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	145/296 (49%)
mdh-2	NP_498457.1	PLN00106	15..333	CDD:215058	155/318 (49%)
		MDH_glyoxysomal_mitochondrial	30..338	CDD:133422	154/308 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161744
Domainoid	1	1.000	185	1.000	Domainoid score	I2012
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D366623at33208
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850