DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10752 and CG12692

DIOPT Version :9

Sequence 1:	NP_648614.1	Gene:	CG10752 / 39467	FlyBaseID:	FBgn0036325	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001284857.1	Gene:	CG12692 / 31372	FlyBaseID:	FBgn0029703	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	470	Identity:	95/470 - (20%)
Similarity:	174/470 - (37%)	Gaps:	111/470 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 RNIGPHAYIIVNDTIYKCQVFVLRIYCKLFTNNLKRGDIVKFPRDAMSNECFELAYTWMTNNAIH 125
            |::|....:.:..:.:.|...:|:.:...|..|:...:..:...|.:: ..|..|||||   .:.
  Fly    57 RSLGAVTRVCIGTSTFWCTSSLLQFHSNYFDRNICPVNCFREGTDLIA-VGFRAAYTWM---RLQ 117

  Fly   126 LP------RDKIINLLAAAKCLQCIPLIKRIFEFLNDYRTHC-----ELFSFSCYLKA-KDMGMT 178
            .|      .||::.||..|..|: :|.:|.:.     |...|     |..:|..||:| |...:.
  Fly   118 EPLDPFMQPDKLMTLLHTAVQLE-MPALKALC-----YEQLCTDRFREETAFQVYLRALKYPQLE 176

  Fly   179 QVADMMVSRVTKSFLVLVSNGQFIKMDIDGACTLLRSRHLAVQNEIEIFYSALLWLISNYEMRIK 243
            ::..:|:.|:..:||.::....|.:|.::...|:|:...|.|.:|:|:..:.:.||....:...:
  Fly   177 ELRKLMLQRIGAAFLAVLGGDDFQRMPLEDVITMLQQDSLGVNSEMEVLVAIIRWLNCQSKCIDQ 241

  Fly   244 YIPRVLSLVRFLMIPAVFILQ-WTSNLKDLRPE--------------------LANVLCHFLHNA 287
            ..|.::..:|..::|...:.: |...:....|:                    :..|..|.||.
  Fly   242 ATPLLMDCLRLTLLPLPILKRFWRCAMAPPVPDEPFMNAVRGNIHIRERISCAITVVQMHHLHT- 305

  Fly   288 MLSQFEYYTETFQSESIIRGNRRWAQDPQC---------PYLSLFNANGDSDLSPDVFFRYLRQI 343
              |:.|:.........::...|.|..|.||         ||..|...:..|:.:.....|.:...
  Fly   306 --SRREFLDFCRSKGLLVDMPREWIYDEQCHYHLPRPGGPYSHLICVHVISNYAIQRAQRLMESS 368

  Fly   344 QNSPKSFVARLIMKDHMEYEIGDALTVNE---------SWTSENSA----EDLKEPGEYNCAV-- 393
            :..|:.....:...|       |..|:||         ..:.|.||    |.|.:|.|.:|.:
  Fly   369 KRWPRRVNTYMPPSD-------DLQTINELPEDKDEEAQVSVEPSAPEMSEGLPQPEEDDCFIAR 426

  Fly   394 ---GGTSSTEDLDAA-----------------------PN-----VKQTFYTSAVELDL--DLLA 425
               |......::.||                       ||     |..|..|.|.:.||  ||..
  Fly   427 LFRGTLLRLNEVMAAQDRNIERRIDNLIRDGTLRPRFIPNAMSRFVLPTAMTCAAQEDLQEDLFL 491

  Fly   426 KNHSVFDSDLDSSES 440
            :. ..:.|:||:.::
  Fly   492 QT-DFYSSNLDAIDA 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10752	NP_648614.1	BACK	172..264	CDD:197943	19/92 (21%)
CG12692	NP_001284857.1	BACK	162..265	CDD:285009	22/102 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006713
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22667
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940