DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14120 and Tengl4

DIOPT Version :9

Sequence 1:	NP_648610.1	Gene:	CG14120 / 39463	FlyBaseID:	FBgn0036321	Length:	1371	Species:	Drosophila melanogaster
Sequence 2:	NP_650038.2	Gene:	Tengl4 / 41321	FlyBaseID:	FBgn0037857	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	63/359 - (17%)
Similarity:	130/359 - (36%)	Gaps:	103/359 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   995 LKDP------APLFVVRSELGHA-----RYLEPNQEGVVQLKHGEALEFHCINSFSGPFSGYTFV 1048
            |.||      .|::...|..||:     ...|.||...:..:.|.:..:   :....|.|...|.
  Fly    38 LTDPYVYQCRQPIYRALSMFGHSSRKSITRTESNQTASIGDESGTSKRY---SERQDPGSVSIFE 99

  Fly  1049 NSTCWQQQ-----------SILAMGSLYQLQDFVCTSWPTYTARRSGRPCNGGTDLLEVGFQLSS 1102
            :...|.::           |:...||.::..:.|                   .|:::.||
  Fly   100 HFLLWGRRKAHNAISKMTLSVGPNGSRHENIEHV-------------------ADIMKYGF---- 141

  Fly  1103 SSSDDF--LQTYDVCHDELSEVTRYVHHVLYPG--SDQYQRSVSRPSFIPGDFYGGKDVNTLYTQ 1163
            ...|:.  .:.:.:.:|..:.:..:|...:..|  .::.::::::|:....|    ..:.|:::.
  Fly   142 PGMDEIHVYKNFVLSYDRRNRIAHWVCEHVKSGCVQERDEKTLNKPNAYITD----NTIPTIFSA 202

  Fly  1164 VQQNITVSEILGMDASPYFNTTGNVYLARGHLSAKTDFVFGAAQ-KASFFFVNAAPQWQTFNGGN 1227
            ..::...|:.:|                 |||::..::...|.: ..::.|.|..|..:......
  Fly   203 NMRDFKNSDWVG-----------------GHLASPQNYKCDALKFLEAYKFTNIVPINRGLKNHI 250

  Fly  1228 WERIEDSVRKFVADENITVDCYTG-----------TWGVSTLPDVNGIGRELYLDFDENNNGLIP 1281
            |.|:|..||. .|.|..:|..|||           .|.|..  .|.|:             ..:.
  Fly   251 WYRLESYVRD-KAIEFDSVHVYTGPLFMPQRITFRNWSVRY--HVMGM-------------NTVA 299

  Fly  1282 VPKLYFRVII--DRESRNGIVLLGVNNPHATIEQ 1313
            ||..:|::||  |..:|:..::.|...|:|.:::
  Fly   300 VPTHFFKIIIREDEFNRDMPIMEGYVVPNAYVDK 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14120	NP_648610.1	NUC	164..416	CDD:238043
		NUC	718..967	CDD:294067
		NUC	1111..1359	CDD:238043	40/219 (18%)
Tengl4	NP_650038.2	Endonuclease_NS	132..362	CDD:279553	45/262 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450454
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940