DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14120 and CG3819

DIOPT Version :9

Sequence 1:	NP_648610.1	Gene:	CG14120 / 39463	FlyBaseID:	FBgn0036321	Length:	1371	Species:	Drosophila melanogaster
Sequence 2:	NP_001262027.1	Gene:	CG3819 / 40069	FlyBaseID:	FBgn0036833	Length:	423	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	189/434 - (43%)
Similarity:	272/434 - (62%)	Gaps:	38/434 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   950 YACSVEDFIEVVKDLPTDQLQTTGILGLTDQILDNEV------CSFKV-NGDLKDPAPLFVVRSE 1007
            :..|.:..|...:|||.:..:.        .:..||:      ||.|: :.:||||.|| :::|:
  Fly    13 FLASAQARILPAEDLPWELPEV--------PVAVNEIEPRAAGCSIKIRSSELKDPQPL-LIKSD 68

  Fly  1008 LGHARYLEPNQEGVVQLKHGEALEFHCINSFSGPFSGYTFVNSTCWQQQSILAMGSLYQLQD--- 1069
            .  :..:..:..|.|.:...:.:||||.:|.:.|.||.: |.:.|       ..|:.:::.|
  Fly    69 T--SEIVGFSDTGYVDVDKDKTIEFHCTSSLASPLSGKS-VTAKC-------VGGTTFKIDDKEH 123

  Fly  1070 ----FVCTSWPTYTARRSGRPCNGGTDLLEVGFQLSSSSSDDFLQTYDVCHDELSEVTRYVHHVL 1130
                ..|||||.:..::||..|||||.|::|||:||.|.   |...|:||.:|..||||||:|.|
  Fly   124 DLSAIKCTSWPVFVGKKSGSSCNGGTTLIKVGFELSGSR---FATQYEVCFNEDEEVTRYVYHRL 185

  Fly  1131 YPGSDQYQRSVSRPSFIPGDFYGGKDVNTLYTQVQQNITVSEILGMDASPYFNTTGNVYLARGHL 1195
            .||::.|...|.|.:|..|.::.||:|:.||||..|..|:.:.|.||:|.:|::..|::|||||:
  Fly   186 EPGNNYYATGVDRITFGAGGYFAGKNVDKLYTQAVQKETIDKELDMDSSRFFDSAKNIFLARGHM 250

  Fly  1196 SAKTDFVFGAAQKASFFFVNAAPQWQTFNGGNWERIEDSVRKFVADENITVDCYTGTWGVSTLPD 1260
            .||.||||...|:|:|.|:||||||||||.|||.|:||.||.:||.||..|:|:||.|||:|||:
  Fly   251 GAKADFVFAPEQRATFLFINAAPQWQTFNAGNWARVEDGVRAWVAKENKHVECWTGVWGVTTLPN 315

  Fly  1261 VNGIGRELYLDFDENNNGLIPVPKLYFRVIIDRESRNGIVLLGVNNPHATIEQIEEEYIICQDIG 1325
            .||..|:|||..|.|.|||||||||||||:|:..::.||||:||||||.::|:|:.:||:|.|:.
  Fly   316 KNGEQRQLYLSHDNNGNGLIPVPKLYFRVVIEPSTKKGIVLIGVNNPHLSLEEIKRDYILCTDVS 380

  Fly  1326 AQLSWVSWTKEDLKKGYSYACTVEDFTAVVKDLPLQDLFVDGVL 1369
            .:::|:||.|.|:..||||||.|.:|...|..||  :..|.|:|
  Fly   381 DRINWISWKKTDITAGYSYACEVPEFRKKVTHLP--EFSVSGLL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14120	NP_648610.1	NUC	164..416	CDD:238043
		NUC	718..967	CDD:294067	5/16 (31%)
		NUC	1111..1359	CDD:238043	133/247 (54%)
CG3819	NP_001262027.1	NUC	164..415	CDD:238043	135/252 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472899
Domainoid	1	1.000	251	1.000	Domainoid score	I4806
eggNOG	1	0.900	-	-		E1_2ANB2
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102209at6960
OrthoFinder	1	1.000	-	-		FOG0014393
OrthoInspector	1	1.000	-	-		mtm9727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850