DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14120 and CG33346

DIOPT Version :9

Sequence 1:	NP_648610.1	Gene:	CG14120 / 39463	FlyBaseID:	FBgn0036321	Length:	1371	Species:	Drosophila melanogaster
Sequence 2:	NP_996301.2	Gene:	CG33346 / 2768690	FlyBaseID:	FBgn0053346	Length:	364	Species:	Drosophila melanogaster

Alignment Length:	363	Identity:	84/363 - (23%)
Similarity:	142/363 - (39%)	Gaps:	68/363 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 HNSYEIIVPDPTDTVRLVNGELLDMFCPGVGFAAPFVNRWQVTATCLQNKYFLVDDLIYPFANFS 129
            :|.||:::.|     :|...:.:.:.|.|        |....|:||..|..|..     |....:
  Fly    44 NNRYELLLTD-----QLQPNQQISLLCDG--------NAQVFTSTCRNNGQFSP-----PLPRTN 90

  Fly   130 CT-AWPIFTALRSGKDCNGGTDLVQVGFEVEDGGFLQSYELCHDAEAEATRYVHHVLYPSS---- 189
            |: |.|......|...|  ...:..|||:. ...|::.|..|:||......:..:.:||::
  Fly    91 CSKAIPPSVVPTSSNIC--PHTMYLVGFKY-GNTFMELYRSCYDARTMKAYFSINTVYPTNLKSD 152

  Fly   190 -----YDYQHGVARPNFLELDFYGGRDVNTKYTQVQQNITISNILGLDASPYFNFSDDRILSRGH 249
                 :| :.|:..|.. |..|    .:|:.|.:.:.      :.| ....|...|......|||
  Fly   153 RPPTVFD-KDGIITPAD-EATF----QMNSIYNRFEY------LFG-SGQTYVPSSRSLSFDRGH 204

  Fly   250 MIAKTDQIFGAAQHTTFLFINVAPQWQTFNGGNWEKVETSVRKFVADRNLTTDCYTGTWGVSTLP 314
            :....|..|......|..::||.||:...|..||:.||..||   ..:::...| ||..||..|.
  Fly   205 LTPVADYSFPKILRQTNKYLNVVPQYYNINRSNWKIVENWVR---GQKDVLNVC-TGALGVLDLL 265

  Fly   315 DVDGIERELYLDFDENNNGLIPVPKIYFRVVIDRVTREGIVLIGINNPYLTLEQIQKDYILCQDI 379
            :.......:||..::|     |||:..::::....|....|::..||.:.|  |......:|:
  Fly   266 NRSQKSVSIYLAPNKN-----PVPRWTYKIIRSLTTGIKYVILTSNNGWET--QQPNPASVCK-- 321

  Fly   380 GHQLSWLTWYKEDLH---EGYSYACSVEDFIEVVKDLP 414
                  :|.....|:   .||::.|...|||.  :::|
  Fly   322 ------VTACPRTLNPTGTGYTFCCDPIDFIR--RNVP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14120	NP_648610.1	NUC	164..416	CDD:238043	61/263 (23%)
		NUC	718..967	CDD:294067
		NUC	1111..1359	CDD:238043
CG33346	NP_996301.2	Endonuclease_NS	124..344	CDD:214889	57/251 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940