DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14120 and cps-6

DIOPT Version :9

Sequence 1:	NP_648610.1	Gene:	CG14120 / 39463	FlyBaseID:	FBgn0036321	Length:	1371	Species:	Drosophila melanogaster
Sequence 2:	NP_491371.1	Gene:	cps-6 / 172045	WormBaseID:	WBGene00000787	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	313	Identity:	65/313 - (20%)
Similarity:	112/313 - (35%)	Gaps:	101/313 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 WPIFTALRSGKDCNGGTDLVQVGFEVEDGGFLQSYELCHDAEAEATRYVHHV---LYPSSYDYQH 194
            :|.||.:|:.:|                  |:.||:.       .||..|.|   |.|....:..
Worm    74 YPGFTNVRTYED------------------FVLSYDY-------KTRTAHWVCEHLTPERLKHAE 113

  Fly   195 GVARPNFLELDFYGGRDVNTKYTQVQQNITISNILGLDASPYFNFSDDRILSRGHMIA----KTD 255
            ||.|                |..:.:.:||..... |..:..:..|.   ..|||:.|    :..
Worm   114 GVDR----------------KLCEFKPDITFPQKF-LSQNTDYKCSG---FDRGHLAAAGNHRKS 158

  Fly   256 QIFGAAQHTTFLFINVAPQ-WQTFNGGNWEKVETSVRKFVADRNLTTDCYTGTWGVSTLPDVDGI 319
            |:   |...||...|::|| .:.||...|..:|...|: ||.:.:.:...||.   ..||.::|
Worm   159 QL---AVDQTFYLSNMSPQVGRGFNRDKWNDLEMHCRR-VAKKMINSYIITGP---LYLPKLEG- 215

  Fly   320 ERELYLDFDENNNGLIPVPKIYFRVVIDRVTREGIVLIGINNPYLTLEQIQKDYILCQDIGHQLS 384
            :.:.|:.:....:..:.||..:|:|.:..||.....|              :.|||...:
Worm   216 DGKKYIKYQVIGDNNVAVPTHFFKVALFEVTPGKFEL--------------ESYILPNAV----- 261

  Fly   385 WLTWYKEDLHEGYSYACSVEDFIEVVK-DLPLEDLHTNGILGLDDVTTVEPST 436
                              :||.:|:.| .:||:.:..:.  ||:....::|.:
Worm   262 ------------------IEDTVEISKFHVPLDAVERSA--GLEIFARLDPKS 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14120	NP_648610.1	NUC	164..416	CDD:238043	55/260 (21%)
		NUC	718..967	CDD:294067
		NUC	1111..1359	CDD:238043
cps-6	NP_491371.1	NUC1	10..308	CDD:224777	65/313 (21%)
cps-6	NP_491371.1	NUC	83..293	CDD:214683	60/301 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910