DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ent3 and Slc29a3

DIOPT Version :9

Sequence 1:	NP_001287052.1	Gene:	Ent3 / 39461	FlyBaseID:	FBgn0036319	Length:	668	Species:	Drosophila melanogaster
Sequence 2:	NP_076085.1	Gene:	Slc29a3 / 71279	MGIID:	1918529	Length:	475	Species:	Mus musculus

Alignment Length:	555	Identity:	124/555 - (22%)
Similarity:	213/555 - (38%)	Gaps:	142/555 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RSRSSHSTTGSGLRRPGSMDSPEFDNRAPKDQRHSVYLALLAAGIGFVLPYNSFIIAADYWQARF 84
            |:.|:|............:|.|....:.|:|:.:..|:.....|||.:||:|.|:.|.:||..:.
Mouse    18 RAPSNHQEADQEALLGKLLDYPAPGLQRPEDRFNGAYIIFFCLGIGGLLPWNFFVTAKEYWAYKL 82

  Fly    85 -----PGR---PVALDMSMTY--------------IFVAFGTVLMNNIVLSVAPFQSRVLFGYMI 127
                 |..   |..:|: :.|              :|:....:|:|.:.:.|     |||....:
Mouse    83 RNCSSPASGEDPEDMDI-LNYFESYLAVASTVPSLLFLVANFLLVNRVQVHV-----RVLASLSV 141

  Fly   128 SF----TTLIFVAVCEVAWHMFATNTAYLVNMSAVALTAIGCTVQQSSFYGFASMLPKQYTQAVM 188
            |.    ..::.|.|...:|    |...:.:.::.:|:.:...|:..||.||.....|.:..||::
Mouse   142 SLAIFVVMIVLVKVDTSSW----TRGFFSLTIACMAIISSSSTIFNSSVYGLTGSFPMRNAQALI 202

  Fly   189 AGESIAGFLVSSNRVVTKLLINND-RVSTVIFFLTSTLYILFSYLLHVATINSPFVRFHVEACSK 252
            :|.::.| .||:..::..|..::| |.||:.|||.:.:::.....|::......:.|::
Mouse   203 SGGAMGG-TVSAVALLVDLAASSDVRDSTLAFFLMAAVFLGLCMGLYLLLSQLEYARYY------ 260

  Fly   253 IVLRPDEQEIDGVPSSTRYGVLSMDGTHTTTTSVGPPGTGNTLSFSNPVYELSNPTAGESSIEAL 317
              :||                            |.|     ...||..    .||:....|..::
Mouse   261 --MRP----------------------------VAP-----VRVFSGE----DNPSQDAPSASSV 286

  Fly   318 GQLPELPATPPAQEPTTPTTVAFKVEHVITPRRCRPSKLGDIREGFVTRWRVAQVIYPHMVCIAL 382
            .....:..|||                 :.|...:.:.||                    .|...
Mouse   287 APASRVMHTPP-----------------LGPILKKTASLG--------------------FCAVS 314

  Fly   383 AYCVTLSLYPGIEVEVQSC--------ALRSWMPVLLMFCFNTSDVVGKILAA---SPYPWSRRQ 436
            .|.||..:.|.|...:||.        ..:.::|:.:...||.:|:.|:.:.|   .|.|.|:
Mouse   315 LYFVTAFIIPAISTNIQSMHKGTGSPWTSKFFVPLTVFLLFNFADLCGRQVTAWIQVPGPRSK-- 377

  Fly   437 LILLSGL---RIVLVPLLLLC-CAPRQ---RPVISGETAPFVFTIALGITNGLAGSLPMMLAPAK 494
              ||.||   |..||||.||| ..||.   :.:...:..|.:||..||::||...:|.::..|..
Mouse   378 --LLPGLVVSRFCLVPLFLLCNYQPRSHLTKVLFQSDIYPVLFTCLLGLSNGYLSTLVLIYGPKI 440

  Fly   495 VPGTLKEVTGNIMTLSYNVGLTVGSLIGYVFESML 529
            ||..|.|.|..:|....:|||.:||....:.|..:
Mouse   441 VPRELAEATSVVMLFYMSVGLMLGSACAALLEHFI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ent3	NP_001287052.1	Nucleoside_tran	60..529	CDD:301621	116/513 (23%)
Slc29a3	NP_076085.1	Nucleoside_tran	57..475	CDD:301621	116/514 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1479
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53699
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820