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Protein Alignment Ent3 and SLC29A3

DIOPT Version :10

Sequence 1:	NP_648608.2	Gene:	Ent3 / 39461	FlyBaseID:	FBgn0036319	Length:	668	Species:	Drosophila melanogaster
Sequence 2:	NP_060814.4	Gene:	SLC29A3 / 55315	HGNCID:	23096	Length:	475	Species:	Homo sapiens

Alignment Length:	547	Identity:	125/547 - (22%)
Similarity:	211/547 - (38%)	Gaps:	142/547 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SRSSHSTTGSGLRRPGS------MDSPEFDNRAPKDQRHSVYLALLAAGIGFVLPYNSFIIAADY 79
            |.|::.||.|.||....      :|.|....:.|:|:....|:...:.|||.:||:|.||.|.:|
Human    13 SNSTYRTTSSSLRADQEALLEKLLDRPPPGLQRPEDRFCGTYIIFFSLGIGSLLPWNFFITAKEY 77

  Fly    80 WQARF-----------PGRPVALDMSMTYIFVAFGTV-----------LMNNIVLSVAPFQS-RV 121
            |..:.           |.....|:...:|:.|| .||           |:|.:.:.:....| .|
Human    78 WMFKLRNSSSPATGEDPEGSDILNYFESYLAVA-STVPSMLCLVANFLLVNRVAVHIRVLASLTV 141

  Fly   122 LFGYMISFTTLIFVAVCEVAWHMFATNTAYLVNMSAVALTAIGCTVQQSSFYGFASMLPKQYTQA 186
            :....:..|.|:.|.........||.....:|.:|..:      ||..||.||.....|.:.:||
Human   142 ILAIFMVITALVKVDTSSWTRGFFAVTIVCMVILSGAS------TVFSSSIYGMTGSFPMRNSQA 200

  Fly   187 VMAGESIAGFLVSSNRVVTKLLINND-RVSTVIFFLTSTLYILFSYLLHVATINSPFVRFHVEAC 250
            :::|.::.| .||:...:..|..::| |.|.:.||||:|::::....|::......:.|:::...
Human   201 LISGGAMGG-TVSAVASLVDLAASSDVRNSALAFFLTATVFLVLCMGLYLLLSRLEYARYYMRPV 264

  Fly   251 SKIVLRPDEQEIDGVPSSTRYGVLSMDGTHTTTTSVGPPGTGNTLSFSNPVYELSNPTAGESSIE 315
            ....:...|:|:                                     |...||.|:.....|:
Human   265 LAAHVFSGEEEL-------------------------------------PQDSLSAPSVASRFID 292

  Fly   316 ALGQLPELPATPPAQEPTTPTTVAFKVEHVITPRRCRPSKLGDIREGFVTRWRVAQVIYPHMVCI 380
            :        .|||.: |....|.:.                     ||               |:
Human   293 S--------HTPPLR-PILKKTASL---------------------GF---------------CV 312

  Fly   381 ALAYCVTLSLYPGIEVEVQSC--------ALRSWMPVLLMFCFNTSDVVGKILAA---SPYPWSR 434
            ...:.:|..:||.|...::|.        ..:.::|:.....:|.:|:.|:.|.|   .|.|.|:
Human   313 TYVFFITSLIYPAICTNIESLNKGSGSLWTTKFFIPLTTFLLYNFADLCGRQLTAWIQVPGPNSK 377

  Fly   435 RQLILLSG---LRIVLVPLLLLC-CAPR---QRPVISGETAPFVFTIALGITNGLAGSLPMMLAP 492
                .|.|   ||..|:||.:|| ..||   :..|...:..|.:.:..||::||...:|.::..|
Human   378 ----ALPGFVLLRTCLIPLFVLCNYQPRVHLKTVVFQSDVYPALLSSLLGLSNGYLSTLALLYGP 438

  Fly   493 AKVPGTLKEVTGNIMTLSYNVGLTVGS 519
            ..||..|.|.||.:|:....:|||:||
Human   439 KIVPRELAEATGVVMSFYVCLGLTLGS 465

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.