Protein Alignment CG10948 and Enox1

DIOPT Version :10

• Sequence 1: NP_729844.1
• Gene: CG10948 / 39459
• FlyBaseID: FBgn0036317
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001240688.1
• Gene: Enox1 / 239188
• MGIID: 2444896
• Length: 662
• Species: Mus musculus
• Alignment Length: 733
• Identity: 251/733 - (34%)
• Similarity: 380/733 - (51%)
• Gaps: 171/733 - (23%)

  Fly   134 SAAGGSTPAASANSTANAQMLMDPTAMMAAAMQQMQQMHYAAAAAAGMTTETGA----GLEATLN 194
            :||.....:.:.::|.....:.||||...|    |..:........|....:.:    |.:..||
Mouse    22 AAAADGLGSIALDTTQLNMSVTDPTAWATA----MNNLGMVPVGLPGQQLVSDSICVPGFDPGLN 82

  Fly   195 -ADGVTP-------------------AGLKEVIKTKNCILFPPNPNAPPPTIRERPPGCRTVFVG 239
             ..|:||                   |.:||:|..|:|.|||.|||.|||:.|||||||:|||||
Mouse    83 MMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVG 147

  Fly   240 GLPENITEEVIREIFESCGEITTLRMSKKNFCHIRYRQEGAIDRAIYLSGYRLRISALNEPPNFG 304
            |||||.|||:|:|:||.||:||.:|.|||||||||:.:|..:|:||||||||:|:.:..:..:.|
Mouse   148 GLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSG 212

  Fly   305 RLHVDYAQARDDQYDYECRQRQHQREQRHRERMSMDRMRSQSPPPIPHYTDHEATTVAEHLRTNE 369
            |||||:||||||.|::||:||...||:|||.::..||:|..|||.|.||::|||..:|:.|:.:.
Mouse   213 RLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLADKLKDDS 277

  Fly   370 TFVKAIQTITAWLERGDCTKRNANVFYSMIQSTHAHVRRLHADKLQLEEDLKKARDSYRNQMGTM 434
            .|.:||..:.:|:|||:..:|:||.||||:||.::|||||..:|...|:::::|:::::|.:..:
Mouse   278 KFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGI 342

  Fly   435 STQFTQIEKVFNAASHKKVWDHFTKAQRKNIDQWKKLATELRTVQ------ITDDDEMEISDDER 493
            .|||.||..||||::.:|.||||:||||||||.|:|.:.|||..|      |..::|||:||||.
Mouse   343 LTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDEN 407

  Fly   494 -----------------------DYDRRGHSAKRIRYDSDGLKDENDSLRCQLEAIRHEMTLERS 535
                                   ..||..||| .:...:..||:||||||.||:|.|:|:.|.:.
Mouse   408 CDSPTKKMRVDESEADIEDCAGDPADRGLHSA-ALAAQAYALKEENDSLRWQLDAYRNEVELLKQ 471

  Fly   536 DYVQ---------REKQIKVLQETIRNMQTQLLQTKLREQKDNKTIEQLERNLKDAGIKQLLLKT 591
            :..|         :::|::.||:|::.||.|||  .::|:.:||..| ||:..::....|.|||.
Mouse   472 EKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLL--AIQEELNNKKSE-LEQAKEEQSHTQALLKV 533

  Fly   592 ---KIKETVDKLRDKEANSAGASNASNASNLDYSSGDSCSREGTEIIRPQAEPEIIDIDKVDDDV 653
               ::|.|.|.:   |.|.
Mouse   534 LQEQLKGTKDLV---ETNG---------------------------------------------- 549

  Fly   654 RIIEHQSGVVEIHEIEDDEKQEPAKDSTKSKANESIMENVSKSNHEETINKSSKEQIPTVAAEEV 718
                        |..||              |||..:..|:..|.:...|...:.|  .:.:|:
Mouse   550 ------------HSHED--------------ANEINVLTVALVNQDRENNTEKRSQ--GLKSEK- 585

  Fly   719 TFKSLVLSEAKIIALASAYLVLHPYGVEIANIASYLSEMLRNNAAPSNHDDLANILGKYTNLFKP 783
                    ||.:|.:.|.:|.:||:|..|..:.||:.::....:|    :::..:|.:...:||.
Mouse   586 --------EALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISA----NEIEMLLMRLPRMFKQ 638

  Fly   784 E--------KEKWRFCGF 793
            |        :::|:.|.|
Mouse   639 EFTGVGATLEKRWKLCAF 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10948	NP_729844.1	RRM_ENOX	228..311	CDD:409675	54/82 (66%)
		SMC_prok_B	404..>606	CDD:274008	88/242 (36%)
		Smc	<512..>740	CDD:440809	55/239 (23%)
Enox1	NP_001240688.1	RRM_ENOX	136..219	CDD:409675	54/82 (66%)
		SMC_prok_B	<291..>601	CDD:274008	117/399 (29%)