Protein Alignment nebu and HXT5

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_011964.1
• Gene: HXT5 / 856496
• SGDID: S000001138
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 582
• Identity: 152/582 - (26%)
• Similarity: 253/582 - (43%)
• Gaps: 75/582 - (12%)

  Fly     2 STASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLL 66
            :.:::|||..|::...:.......:..|..|:..:.|.|.:              ..|.|:...|
Yeast    17 TVSTNSNSYNEKSGNSTAPGTAGYNDNLAQAKPVSSYISHE--------------GPPKDELEEL 67

  Fly    67 GNMVHTSTSNNSQKWPQYVA--ALAAAGGAFA----AGTVLGWTSPAETEIV-----DRGEGYDF 120
            ...|.......|:....:|:  .|..|.|.|.    .||:.|:.  .:|:.:     .|..|..:
Yeast    68 QKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFGWDTGTISGFV--RQTDFIRRFGSTRANGTTY 130

  Fly   121 PVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLY--- 182
            ..|. :...:.|...:|.|...|.:..|.:|.|||..::.:|:.:.:|  ::|...::...|
Yeast   131 LSDV-RTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIG--IIIQIASIDKWYQYF 192

  Fly   183 ASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICG 247
            ..|.|.|:..|...|.|||...|::.|::||||.|.:|||||.||...|....|.|.:..|:...
Yeast   193 IGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWR 257

  Fly   248 I-LPLIFG-AIFF-----FMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETK 305
            : |.|.|. :||.     |:||||.|||...:.|.|.:|:........|......|:.......:
Yeast   258 VPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIE 322

  Fly   306 ANKVNVWAALNRPVT------RKALAISMGLMF--FQQVCGINAVIFYASRIFLEANTGIEAEWA 362
            |.::...|:....||      |:.|   ||:|.  .||:.|.|...:|.:.||  ...|:|..:.
Yeast   323 AERLAGSASWGELVTGKPQMFRRTL---MGMMIQSLQQLTGDNYFFYYGTTIF--QAVGLEDSFE 382

  Fly   363 T-ILIGIMQVVATFVSTLVVDKLGRRILLLASGISMA---ISTTAIGV-YFFLQKQDAAQVVSLG 422
            | |::|::..|:||.|...||:.|||..||...:.|.   :...::|| ..:...||.......|
Yeast   383 TAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAG 447

  Fly   423 WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVT------KTFVN 481
            ...:...|.:|..|:..:.||.::::.|.:...::|.|.|:|...||:..|:::      .:.:|
Yeast   448 NCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAIN 512

  Fly   482 LNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGN----RSTPQAIPAEK 539
            ...|       ::|.|..|....:|:|.||||||.:|.|:.:....|    :||....|:.:
Yeast   513 FYYG-------YVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	128/454 (28%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	134/476 (28%)