Protein Alignment nebu and HXT1

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 547
• Identity: 142/547 - (25%)
• Similarity: 239/547 - (43%)
• Gaps: 64/547 - (11%)

  Fly    16 KKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTS-NNSQ 79
            :||.|:|   |:.|||..:.|           ..:..|:..|. ||  ||..:.|..:.: .|:.
Yeast    11 QKSNSSN---SYELESGRSKA-----------MNTPEGKNESF-HD--NLSESQVQPAVAPPNTG 58

  Fly    80 KWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDR-------GEGYDFPVDKDQFSWVG 131
            |......::.....|| .|.:.||.:      .|:|:.:.|       |..|   :.|.:...:.
Yeast    59 KGVYVTVSICCVMVAF-GGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHY---LSKVRTGLIV 119

  Fly   132 SAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLY-ASRFILGIAGGAF 195
            |...:|.|...|.:..|.:|.||:..::.:|:.:.:|..:.|.::|....| ..|.|.|:..|..
Yeast   120 SIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGI 184

  Fly   196 CVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSI-------ICGILPLIF 253
            .|.:||...|:|..|:||||.|.:|:|||:||...|....|.|.:..|:       :|....|..
Yeast   185 TVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFM 249

  Fly   254 GAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDY---EPELAELRETDRETKANKVNVWAAL 315
            .....|:||||.|||...|.:.|..|:..:.....|:   :.||..:..:..|.:|.....|..|
Yeast   250 IGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGEL 314

  Fly   316 --NRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWAT-ILIGIMQVVATFVS 377
              .:|...:...:.:.:...||:.|.|...:|.:.:|  ...|:...:.| |:.|::...:|..|
Yeast   315 FTGKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVF--QAVGLSDSFETSIVFGVVNFFSTCCS 377

  Fly   378 TLVVDKLGRRILLLASGISMA---ISTTAIGV-YFFLQKQDAAQVVSLGWLPVASLCLFIIMFSI 438
            ...||:.|||..|:...:.|.   :...::|| ..:...||.......|...:...|.:|..|:.
Yeast   378 LYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFAT 442

  Fly   439 GYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVT--KTFVN--LNDGLGIGGTFWLFAGLT 499
            .:.|:.::::.|.|...:|....|:|..:||:..|:::  ..|:.  :|...|     ::|.|..
Yeast   443 TWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYG-----YVFMGCM 502

  Fly   500 VVGVIFVYFAVPETKGKSLNEIQQELA 526
            |....:|:|.||||||.||.|:....|
Yeast   503 VFAYFYVFFFVPETKGLSLEEVNDMYA 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	119/455 (26%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	123/470 (26%)