Protein Alignment nebu and HXT4

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_011960.2
• Gene: HXT4 / 856492
• SGDID: S000001134
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 586
• Identity: 158/586 - (26%)
• Similarity: 254/586 - (43%)
• Gaps: 104/586 - (17%)

  Fly    22 NEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPH---DQENLLGNMVHTSTSNNSQKWPQ 83
            :||:::..::|.......:..||:    ||:....|||.   :::::.....:...|||..:.|:
Yeast     2 SEEAAYQEDTAVQNTPADALSPVE----SDSNSALSTPSNKAERDDMKDFDENHEESNNYVEIPK 62

  Fly    84 -----YV----AALAAAGGAFA----AGTVLGWTSPAETEIVDR-------GEGYDFPVDKDQFS 128
                 ||    ..|..|.|.|.    .||:.|:.  |:|:.:.|       |..|   :.|.:..
Yeast    63 KPASAYVTVSICCLMVAFGGFVFGWDTGTISGFV--AQTDFIRRFGMKHHDGTYY---LSKVRTG 122

  Fly   129 WVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLY-ASRFILGIAG 192
            .:.|...:|.|...|.:..|.:|.|||..::.:|:.:|:|..:.|.::|....| ..|.|.|:..
Yeast   123 LIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGV 187

  Fly   193 GAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFG--- 254
            |...|.:||...|::.|.|||||.|.:|||||:||...|....|.|.:..|:...: ||..|
Yeast   188 GGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRV-PLGLGFAW 251

  Fly   255 AIFF-----FMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKV--NV- 311
            |:|.     |:||||.|||...:.|.|.:||........|....:||:.......:|.|:  |.
Yeast   252 ALFMIGGMTFVPESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNAS 316

  Fly   312 WAALNRPVTRKALAISMGLMF--FQQVCGINAVIFYASRIFLEANTGIEAEWAT-ILIGIMQVVA 373
            |..:....|:....:.||.|.  .||:.|.|...:|.:.:|  ...|:|..:.| |::||:...:
Yeast   317 WGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVF--TAVGLEDSFETSIVLGIVNFAS 379

  Fly   374 TFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGW--------------L 424
            |||...:|::.|||..||....||    ||..|.|      |:..|:..|              .
Yeast   380 TFVGIFLVERYGRRRCLLWGAASM----TACMVVF------ASVGVTRLWPNGKKNGSSKGAGNC 434

  Fly   425 PVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIG 489
            .:...|.::..|:..:.|:|:::..|.|...:|....::|...||:..|::
Yeast   435 MIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLI-------------- 485

  Fly   490 GTF-------------WLFAGLTVVGVIFVYFAVPETKGKSLNEIQ---QELAGNRSTPQAIPAE 538
            |.|             ::|.|..|....:|:|.||||||.:|.|:.   :|......:|..:|..
Yeast   486 GFFTPFISGAIDFYYGYVFMGCLVFSYFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPN 550

  Fly   539 K 539
            |
Yeast   551 K 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	132/469 (28%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	138/491 (28%)