Protein Alignment CG10960 and VBA5

DIOPT Version :9

• Sequence 1: NP_648605.1
• Gene: CG10960 / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_013031.3
• Gene: VBA5 / 853980
• SGDID: S000001813
• Length: 582
• Species: Saccharomyces cerevisiae
• Alignment Length: 645
• Identity: 127/645 - (19%)
• Similarity: 206/645 - (31%)
• Gaps: 260/645 - (40%)

  Fly    37 KYGSRQPVKIVKASD---NGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAG 98
            ||.|:|.::....||   |.|.|:     ::.:|..::...:  |.....::.||    .....|
Yeast     5 KYSSQQEIEGACGSDASLNARGSN-----DSPMGLSLYLCLA--SLTLVLFITAL----DILIVG 58

  Fly    99 TVL-------------GWTSPAETEIVDRGEGYDFPVDKDQFSW------VGSAMTLGAACVCIP 144
            |::             ||..          .||..|.......|      :|...:|..|.:...
Yeast    59 TIIDVVAEQFGNYSKTGWLV----------TGYSLPNAILSLIWGRFASIIGFQHSLILAILIFE 113

  Fly   145 IGFLINMIGRKWTMLFL-------------VLPFILGWTM-------LIWAVNVSMLYASRFILG 189
            .|.||..:.....||..             .|.|::|.||       |:.:: :|..:|...|:|
Yeast   114 AGSLIAALASSMNMLIFGRVVAGVGGSGLQTLCFVIGCTMVGERSRPLVISI-LSCAFAVAAIVG 177

  Fly   190 -IAGGAF--------C--VTAPM-----------YTGE---IAQ--KEIRGTLGSF----FQLMI 223
             |.||||        |  :..|:           |..|   |.|  |:..||:.||    |:..:
Yeast   178 PIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKGILQQIKDAIGTISSFTFSKFRHQV 242

  Fly   224 TI-----GILFVY------AVGAGVKIF------------WLS------IICGILPLIFGAIFFF 259
            ..     ||:|.:      ...||:.:|            |.|      ::.|:|..||..::.|
Yeast   243 NFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFGGNKYSWNSGQVITYLVLGVLLFIFSLVYDF 307

  Fly   260 MPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNVWAALNRPVTRKAL 324
                  :|..|                 ::.||:....|.             ..|.|.|.:.|:
Yeast   308 ------FLFDK-----------------FNPEPDNISYRP-------------LLLRRLVAKPAI 336

  Fly   325 AISMGLMFFQQVCGINAVIFYASRIF--LEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGR- 386
            .| :.::.|....|.|..:.|:.:.|  :.|::..:|....|.|.|..|:|...|.::..|||.
Yeast   337 II-VNMVTFLLCTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGVITKKLGLV 400

  Fly   387 RILLLASGI-------------SMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSI 438
            :.||:..|:             :.:..:|.|||                        |.:..||:
Yeast   401 KPLLIFGGVLGVIGAGLMTLMTNTSTKSTQIGV------------------------LLLPGFSL 441

  Fly   439 GYGPVPWLMMGEL------------------FATDIKGFAGSLAGTSNWLLAFVVTKTFVN---- 481
            |:.....||..:|                  |.|.:|....:|.|.   |...|.:.:|.|
Yeast   442 GFALQASLMSAQLQITKDRPEAAMDFIEVTAFNTFMKSLGTTLGGV---LSTTVFSASFHNKVSR 503

  Fly   482 --------------------------------LNDGLGIGGTFWLFAGLTVVGVIFVYFA 509
                                            |:|  .|...||:..|...:|.:|..|:
Yeast   504 AHLEPYEGKTVDDMILYRLQNYDGSHSTIGNILSD--SIKNVFWMDLGFYALGFLFCSFS 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	98/476 (21%)
		MFS	118..508	CDD:119392	108/545 (20%)
VBA5	NP_013031.3	MFS_Azr1_MDR_like	43..493	CDD:341045	104/528 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900