Protein Alignment nebu and HXT9

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_012316.1
• Gene: HXT9 / 853236
• SGDID: S000003755
• Length: 567
• Species: Saccharomyces cerevisiae
• Alignment Length: 602
• Identity: 143/602 - (23%)
• Similarity: 244/602 - (40%)
• Gaps: 149/602 - (24%)

  Fly    18 SGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPH-DQENLLGNMVHTSTSNNSQKW 81
            ||.||..::.|..:..|.....:...||            |.| |.:|.| |:..|....:..:.
Yeast     2 SGVNNTSANDLSTTESNSNSVANAPSVK------------TEHNDSKNSL-NLDATEPPIDLPQK 53

  Fly    82 P--QY----VAALAAAGGAFAAGTVLGWTSPAETEIV-------------DRGEGYDFPVDKDQF 127
            |  .|    :..|..|.|.|    :.||.:...:..|             |:|..|   :.|.:.
Yeast    54 PLSAYTTVAILCLMIAFGGF----IFGWDTGTISGFVNLSDFIRRFGQKNDKGTYY---LSKVRM 111

  Fly   128 SWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLY-ASRFILGIA 191
            ..:.|...:|.|...|.:..:.::.||:..::.:...:::|..:.|.::|....| ..|.|.|:.
Yeast   112 GLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLG 176

  Fly   192 GGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYA---------------VGAGVKIFW 241
            .|...|.:||...|:|.|:|||||...:|||.|:||...|.               ||.|:...|
Yeast   177 VGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAW 241

  Fly   242 LS-IICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETK 305
            .: ::.|::         |:||||.||:...:.|.|.:|:                       :|
Yeast   242 TTFMVSGMM---------FVPESPRYLIEVGKDEEAKRSL-----------------------SK 274

  Fly   306 ANKVNV--------------------------WAALNRPVTRKALAISMGLMF--FQQVCGINAV 342
            :|||:|                          |:.|....|:....:.||:|.  .||:.|.|..
Yeast   275 SNKVSVDDPALLAEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYF 339

  Fly   343 IFYASRIFLEANTGIEAEWAT-ILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAIS---TTA 403
            .:|.:.||  .:.|::..:.| |:||::...::|::...:::.|||..||....||...   ..:
Yeast   340 FYYGTTIF--KSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFAS 402

  Fly   404 IGV-YFFLQKQDAAQVVSLGWLPVASLCL------FIIMFSIGYGPVPWLMMGELFATDIKGFAG 461
            :|| ..:.|......:.|.|    |..|:      ||..|:..:....::::.|.|...:|....
Yeast   403 VGVTKLWPQGSSHQDITSQG----AGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGM 463

  Fly   462 SLAGTSNWLLAFVVT--KTFVN--LNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQ 522
            ::|..:||:..|:::  ..|:.  :|...|     ::|.|..|....:|:|.||||||.:|.|:
Yeast   464 AIATAANWMWGFLISFFTPFITGAINFYYG-----YVFLGCLVFAYFYVFFFVPETKGLTLEEV- 522

  Fly   523 QELAGNRSTPQAIPAEK 539
                 |....:.:||.|
Yeast   523 -----NTMWLEGVPAWK 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	117/493 (24%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	123/517 (24%)