Protein Alignment nebu and MAL11

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_011805.3
• Gene: MAL11 / 853207
• SGDID: S000003521
• Length: 616
• Species: Saccharomyces cerevisiae
• Alignment Length: 648
• Identity: 140/648 - (21%)
• Similarity: 241/648 - (37%)
• Gaps: 182/648 - (28%)

  Fly     1 MSTASSSNSSGEEANKKSGSNNEESSHLL---------ESAENGAKYGSRQPVKIVKASDNGRTS 56
            |....|..|..:.|:|....|..|||..:         |..|.|.|..:.:...:...:::.:..
Yeast     1 MKNIISLVSKKKAASKNEDKNISESSRDIVNQQEVFNTEDFEEGKKDSAFELDHLEFTTNSAQLG 65

  Fly    57 STPHDQENLLGNMVHTSTSN--NSQ-----------KWPQYVAALAAAGGAFAAGTVLGWTSPAE 108
            .:..|.||::..|..|..:|  ||:           |:|:  |||              |:....
Yeast    66 DSDEDNENVINEMNATDDANEANSEEKSMTLKQALLKYPK--AAL--------------WSILVS 114

  Fly   109 TEIVDRGEGYD---------FPVDKDQFSW--------VGSAMTLGAACVCIPIG---------F 147
            |.:|  .||||         .||.:.:|..        :.|...:|.. :|:..|         :
Yeast   115 TTLV--MEGYDTALLSALYALPVFQRKFGTLNGEGSYEITSQWQIGLN-MCVLCGEMIGLQITTY 176

  Fly   148 LINMIGRKWTM---LFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQK 209
            ::..:|.::||   |.|:..:|.   :|.:..:::|:...:.:..|..|.|...|..|..|:...
Yeast   177 MVEFMGNRYTMITALGLLTAYIF---ILYYCKSLAMIAVGQILSAIPWGCFQSLAVTYASEVCPL 238

  Fly   210 EIRGTLGSFFQLMITIGILFV-----------------YAVGAGVKIFWLSIICGILPLIFGAIF 257
            .:|..:.|:..:....|.:|.                 |.:...::..|.:      ||:.|  .
Yeast   239 ALRYYMTSYSNICWLFGQIFASGIMKNSQENLGNSDLGYKLPFALQWIWPA------PLMIG--I 295

  Fly   258 FFMPESPTYLVSKDRSENAIKSIQWL---RGKEYDYEPELA----ELRETDRETKANK----VNV 311
            ||.||||.:||.|||...|.||:..:   :|.|.|.:.:|.    ||........|:|    .|.
Yeast   296 FFAPESPWWLVRKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQIELTIEKERLLASKSGSFFNC 360

  Fly   312 WAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIG-IMQVVATF 375
            :..:|...||.|.     |.:..|......::.|::..|..|....:..:...||. .:.:..|.
Yeast   361 FKGVNGRRTRLAC-----LTWVAQNSSGAVLLGYSTYFFERAGMATDKAFTFSLIQYCLGLAGTL 420

  Fly   376 VSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFII------ 434
            .|.::..::||..:|            ..|:.|        |:|          |||||
Yeast   421 CSWVISGRVGRWTIL------------TYGLAF--------QMV----------CLFIIGGMGFG 455

  Fly   435 ------------------MFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAF---VVTKT 478
                              .::.|.|.|.:.::.|:.:.:::.....||.....|:|.   ::|..
Yeast   456 SGSSASNGAGGLLLALSFFYNAGIGAVVYCIVAEIPSAELRTKTIVLARICYNLMAVINAILTPY 520

  Fly   479 FVNLND-GLGI-GGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK 539
            .:|::| ..|. .|.:|  .|.|.|.:.:|...:|||.|::.:||      |....|.:||.|
Yeast   521 MLNVSDWNWGAKTGLYW--GGFTAVTLAWVIIDLPETTGRTFSEI------NELFNQGVPARK 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	107/507 (21%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	116/548 (21%)