DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10960 and STL1

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_010825.3	Gene:	STL1 / 852149	SGDID:	S000002944	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	503	Identity:	127/503 - (25%)
Similarity:	220/503 - (43%)	Gaps:	71/503 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 NLLGNMV-HTSTSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQF 127
            |..|..: .||....:.|..:|...:|:..|....|...|..:   :.|..:...|:||..|:..
Yeast     8 NFKGKFISRTSHWGLTGKKLRYFITIASMTGFSLFGYDQGLMA---SLITGKQFNYEFPATKENG 69

  Fly   128 SWVGSAMTL-GAACVCIPIG---------FLINMIGRKWTMLFLVLPFILGWTML------IWAV 176
            .....|..: ||...|..:|         |....||||..:|...:..|:|..:.      .||:
Yeast    70 DHDRHATVVQGATTSCYELGCFAGSLFVMFCGERIGRKPLILMGSVITIIGAVISTCAFRGYWAL 134

  Fly   177 NVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGV---- 237
            ...::  .|.:.|:..|....|.|::..|:::.|.||.|.:.....|..|.:..|.:..|:
Yeast   135 GQFII--GRVVTGVGTGLNTSTIPVWQSEMSKAENRGLLVNLEGSTIAFGTMIAYWIDFGLSYTN 197

  Fly   238 -KIFW-----LSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEP---- 292
             .:.|     :.|:..:..|.|   ...:||||.:|:|:.|:|.|    ::|.|...|.:|
Yeast   198 SSVQWRFPVSMQIVFALFLLAF---MIKLPESPRWLISQSRTEEA----RYLVGTLDDADPNDEE 255

  Fly   293 ---ELAELRETDRETKANKVNVWAALNRPVT---RKALAISMGLMFFQQVCGINAVIFYASRIFL 351
               |:|.|.:....||..|.::.:..:|..:   ::|| |:....||||..|.||.|:|::.:|
Yeast   256 VITEVAMLHDAVNRTKHEKHSLSSLFSRGRSQNLQRAL-IAASTQFFQQFTGCNAAIYYSTVLF- 318

  Fly   352 EANTGIEAEW-ATILIG----IMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQ 411
              |..|:.:: .:::||    .:..::|..|..:::|||||.|.|......|:|.|........:
Yeast   319 --NKTIKLDYRLSMIIGGVFATIYALSTIGSFFLIEKLGRRKLFLLGATGQAVSFTITFACLVKE 381

  Fly   412 KQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVV- 475
            .::.|:..::|      |.|||..|.:....:||:...|:.:..::....:.:..:|||..|.|
Yeast   382 NKENARGAAVG------LFLFITFFGLSLLSLPWIYPPEIASMKVRASTNAFSTCTNWLCNFAVV 440

  Fly   476 --TKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEI 521
              |..|:    |....|.:..||.:..:.:..::|..|||.|:||.||
Yeast   441 MFTPIFI----GQSGWGCYLFFAVMNYLYIPVIFFFYPETAGRSLEEI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	99/397 (25%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	107/433 (25%)
STL1	NP_010825.3	Sugar_tr	32..488	CDD:395036	121/479 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.810