Protein Alignment nebu and ITR1

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 547
• Identity: 154/547 - (28%)
• Similarity: 240/547 - (43%)
• Gaps: 58/547 - (10%)

  Fly     8 NSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHT 72
            |:...|.|.:..|.::.....|||.|.     .|.|.    :.|..|....|.:.|:....|:
Yeast    23 NADSVEFNSEHDSPSKRGKITLESHEI-----QRAPA----SDDEDRIQIKPVNDEDDTSVMI-- 76

  Fly    73 STSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPV----DKDQFSWVGSA 133
             |.|.|...........|:...|..|...|:.|.|   ::..|...|..|    :|:   .|.:|
Yeast    77 -TFNQSLSPFIITLTFVASISGFMFGYDTGYISSA---LISIGTDLDHKVLTYGEKE---IVTAA 134

  Fly   134 MTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVT 198
            .:|||....|..|...::.|||..::...|.|::|..:.:.|.....:...|.|:|...|...:.
Yeast   135 TSLGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLI 199

  Fly   199 APMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIF---WLSIICGILPLIFGAIFF-- 258
            ||::..|||.|.|||.|.....|.:|.|.|..|..|||:...   | .|:.| |.||..|:.|
Yeast   200 APLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGW-RILVG-LSLIPTAVQFTC 262

  Fly   259 --FMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKV-------NVWAA 314
              |:|::|.|.|.|.   :..::.:.|:....|...|:.|.:..:..|....:       .||..
Yeast   263 LCFLPDTPRYYVMKG---DLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKVWNT 324

  Fly   315 LNR----PVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWA-TILIGIMQVVAT 374
            :..    |...:||.|..||...||..|.|::::::..||  ...|.:...| :|::.....:.|
Yeast   325 IKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIF--ETVGFKNSSAVSIIVSGTNFIFT 387

  Fly   375 FVSTLVVDKLGRRILLLAS--GISMAISTTAIGVYFFLQKQDAAQVV-------SLGWLPVASLC 430
            .|:...:||:|||.:||..  |::||:...:|..:|...|.|.|..|       |.|.:.:..:.
Yeast   388 LVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVIIVFII 452

  Fly   431 LFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLF 495
            :|...:::|.|.||| ...|||..:::|...|.|..:||..:.|:..||:.:...:...|||..|
Yeast   453 VFAAFYALGIGTVPW-QQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPAGTFAFF 516

  Fly   496 AGLTVVGVIFVYFAVPETKGKSLNEIQ 522
            |||:.:..||.||..||..|..|.|:|
Yeast   517 AGLSCLSTIFCYFCYPELSGLELEEVQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	131/452 (29%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	130/454 (29%)