Protein Alignment nebu and RGT2

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_010143.1
• Gene: RGT2 / 851417
• SGDID: S000002297
• Length: 763
• Species: Saccharomyces cerevisiae
• Alignment Length: 583
• Identity: 163/583 - (27%)
• Similarity: 255/583 - (43%)
• Gaps: 90/583 - (15%)

  Fly    23 EESSHLLESAENGAKYGSRQPVKIV-----KASDNGRTSSTPHDQENLL-----GNMVHTSTSNN 77
            ||:|||    ..|..:|..|..:..     ....|..|.||...:...:     .|....|.:||
Yeast    12 EENSHL----NPGNDFGHHQGAECTINHNNMPHRNAYTESTNDTEAKSIVMCDDPNAYQISYTNN 72

  Fly    78 ---------------SQKWPQYVAALAAAGGAFAA--GTVLGWTSPAETEIVDRG--EGYDFP-- 121
                           ||..|.....::...|.|.|  |.:.|:.:.....|.|..  :.|..|
Yeast    73 EPAGDGAIETTSILLSQPLPLRSNVMSVLVGIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNH 137

  Fly   122 --VDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLF-LVLPFILGWTMLIWAVNVSMLYA 183
              ....|.:.:.|.::||.....:...::.:..|||.|::| ..:.|.:|.::.:.:..:.:|..
Yeast   138 SYFTTSQIAILVSFLSLGTFFGALIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLVLLIV 202

  Fly   184 SRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILF---------------VYAV 233
            .|.|.||..|......|:|..|.|||.:||.:.|.:|..||||:|.               .|.:
Yeast   203 GRVISGIGIGIISAVVPLYQAEAAQKNLRGAIISSYQWAITIGLLVSSAVSQGTHSKNGPSSYRI 267

  Fly   234 GAGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEP----EL 294
            ..|::..|.||      |..|.|  |:||||.|.|.||....|.||:.:|||...: :|    ||
Yeast   268 PIGLQYVWSSI------LAVGMI--FLPESPRYYVLKDELNKAAKSLSFLRGLPIE-DPRLLEEL 323

  Fly   295 AELRET-DRETKANKVNVW----AALNRPVTRKALAISMGLMF--FQQVCGINAVIFYASRIFLE 352
            .|::.| |.|.......:.    .:.|||  ::.|.|..|:..  |||..|||.:.:|....|
Yeast   324 VEIKATYDYEASFGPSTLLDCFKTSENRP--KQILRIFTGIAIQAFQQASGINFIFYYGVNFF-- 384

  Fly   353 ANTGIEAEWATILIG-IMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAA 416
            .|||::..:....|. .:.|..:.....:||::|||.:|||.|:.|||:...|.:....:    .
Yeast   385 NNTGVDNSYLVSFISYAVNVAFSIPGMYLVDRIGRRPVLLAGGVIMAIANLVIAIVGVSE----G 445

  Fly   417 QVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAF---VVTKT 478
            :.|....:.:|.:||||..||..:|.|.|::..||:...::....::...:|||:.|   ::|..
Yeast   446 KTVVASKIMIAFICLFIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALITPY 510

  Fly   479 FVNLNDGLGIGG--TFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK 539
            .|::.......|  .|:::.||.||.||.|||||.||:|.:|.||.:..   |..|.::.:.|
Yeast   511 IVDVGSHTSSMGPKIFFIWGGLNVVAVIVVYFAVYETRGLTLEEIDELF---RKAPNSVISSK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	135/459 (29%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	142/495 (29%)