Protein Alignment nebu and MPH2

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_010034.1
• Gene: MPH2 / 851350
• SGDID: S000002406
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 490
• Identity: 115/490 - (23%)
• Similarity: 197/490 - (40%)
• Gaps: 100/490 - (20%)

  Fly   103 WTSPAETEIVDRGEGYD---------FPVDKDQF--------SWVGSAMTLGAACVCIPIGFL-- 148
            |:....|.::  .||||         .|:.:.:|        .|..||.......:|...|.:
Yeast   100 WSLLVSTTLI--MEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVG 162

  Fly   149 -------INMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAF-CVTAPMYTG 204
                   ::::|.::| |.:.|.|:..:|.:::..| :.|:...:.:.|:..|.| |:|. .|..
Yeast   163 LQLTGPSVDLVGNRYT-LIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTV-SYAS 225

  Fly   205 EIAQKEIRGTLGSFFQLMITIGILFVYAV-----------GAGVKI-FWLSIICGILPLIFGAIF 257
            ||....:|..|.::..|....|.||...:           ..|.|: |.|..|..: ||..|  .
Yeast   226 EICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPV-PLALG--I 287

  Fly   258 FFMPESPTYLVSKDRSENAIKSI-QWLRGKEYDYE----PELAELRET-DRETK-ANKVNVWA-- 313
            ||.||||.:||.|.|.:.|.:|: :.|.||..:.|    .|:.:::.| |:|.: .:|...::
Yeast   288 FFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDC 352

  Fly   314 ---ALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWA-TILIGIMQVVAT 374
               .:||..||.......|    |..|| :.:|.|::..:.:|....|..:. :|:...:.:.||
Yeast   353 FEDKINRRRTRITCLCWAG----QATCG-SILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICAT 412

  Fly   375 FVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVAS----------- 428
            |:|.......||..|.   ...:|..|    :.||:          :|.|..:|
Yeast   413 FLSWWASKYFGRYDLY---AFGLAFQT----IVFFI----------IGGLGCSSTHGSKMGSGSL 460

  Fly   429 LCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLA-GTSNWLLAFVVTKTFVNLND---GLGI- 488
            |......:::|..||.:.::.|:.::.::.....|| .|.|.:...........||.   ..|.
Yeast   461 LMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAK 525

  Fly   489 GGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQ 523
            .|.||  ..|....:|:....:|||.||:..||.:
Yeast   526 SGFFW--GVLCFCTLIWAVVDLPETAGKTFVEINE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	113/485 (23%)
MPH2	NP_010034.1	SP	72..556	CDD:273317	113/486 (23%)