DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and ERDL6

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_177658.1	Gene:	ERDL6 / 843859	AraportID:	AT1G75220	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	177/514 - (34%)
Similarity:	255/514 - (49%)	Gaps:	48/514 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NNEESSHLLES--AENGAKY--GSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQKW 81
            :|||:.:.|..  ...|:.|  ||||                        .:|:.:|........
plant     6 DNEEARNDLRRPFIHTGSWYRMGSRQ------------------------SSMMGSSQVIRDSSI 46

  Fly    82 PQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIG 146
            ......|..|.|....|...|::||.:..|..     |..:...::|..||...:||....|..|
plant    47 SVLACVLIVALGPIQFGFTCGYSSPTQAAITK-----DLGLTVSEYSVFGSLSNVGAMVGAIASG 106

  Fly   147 FLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEI 211
            .:...||||.:::...:|.|:||..:.:|.:.|.||..|.:.|...|....|.|:|..|||.:.:
plant   107 QIAEYIGRKGSLMIAAIPNIIGWLCISFAKDTSFLYMGRLLEGFGVGIISYTVPVYIAEIAPQNM 171

  Fly   212 RGTLGSFFQLMITIGILFVYAVGAGVKIFW-LSIICGILP---LIFGAIFFFMPESPTYLVSKDR 272
            ||.|||..||.:||||:..|.:|..|.  | :..:.||||   ||.|  .||:||||.:|.....
plant   172 RGGLGSVNQLSVTIGIMLAYLLGLFVP--WRILAVLGILPCTLLIPG--LFFIPESPRWLAKMGM 232

  Fly   273 SENAIKSIQWLRGKEYDYEPELAEL-RETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQV 336
            ::....|:|.|||.|.|...|:.|: |.....||.|.|. :..|.|......|.:.:||:..||:
plant   233 TDEFETSLQVLRGFETDITVEVNEIKRSVASSTKRNTVR-FVDLKRRRYYFPLMVGIGLLVLQQL 296

  Fly   337 CGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAIST 401
            .|||.|:||:|.||..|.. ..:..||..:|.:|||||.:||.:|||.|||:||..|.:.|.||.
plant   297 GGINGVLFYSSTIFESAGV-TSSNAATFGVGAIQVVATAISTWLVDKAGRRLLLTISSVGMTISL 360

  Fly   402 TAIGVYFFLQKQDAAQVVSLGWLPVAS---LCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSL 463
            ..:...|:|::..:.......||.:.|   :...::.||:|.||:|||:|.|:...:|||.|||:
plant   361 VIVAAAFYLKEFVSPDSDMYSWLSILSVVGVVAMVVFFSLGMGPIPWLIMSEILPVNIKGLAGSI 425

  Fly   464 AGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQ 522
            |..:||..::::|.| .||......||||.|:..:....|:||...|||||||:|.|:|
plant   426 ATLANWFFSWLITMT-ANLLLAWSSGGTFTLYGLVCAFTVVFVTLWVPETKGKTLEELQ 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	135/364 (37%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	147/397 (37%)
ERDL6	NP_177658.1	MFS_GLUT6_8_Class3_like	49..481	CDD:340916	163/443 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.820