DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and AT1G19450

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_173377.1	Gene:	AT1G19450 / 838529	AraportID:	AT1G19450	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	174/522 - (33%)
Similarity:	258/522 - (49%)	Gaps:	48/522 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SGEEANKKSGSNNEESSHLLESAENGAKY--GSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHT 72
            |..:.|.:.|.|:.....|    ..|:.|  ||||                        .:|:.:
plant     2 SFRDDNTEEGRNDLRRPFL----HTGSWYRMGSRQ------------------------SSMLES 38

  Fly    73 STSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLG 137
            |..............|..|.|....|...|::||.:..|..     |..:...::|..||...:|
plant    39 SQVIRDSSISVLACVLIVALGPIQFGFTCGYSSPTQAAITK-----DLGLTVSEYSVFGSLSNVG 98

  Fly   138 AACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMY 202
            |....|..|.:...:|||.:::...:|.|:||..:.:|.:.|.||..|.:.|...|....|.|:|
plant    99 AMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLSISFAKDTSFLYMGRLLEGFGVGIISYTVPVY 163

  Fly   203 TGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFW-LSIICGILP---LIFGAIFFFMPES 263
            ..|||.:.:||.|||..||.:||||:..|.:|..|.  | :..:.|:||   ||.|  .||:|||
plant   164 IAEIAPQTMRGALGSVNQLSVTIGIMLAYLLGLFVP--WRILAVLGVLPCTLLIPG--LFFIPES 224

  Fly   264 PTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNVWAALNRPVTRKALAISM 328
            |.:|.....:::...|:|.|||.|.|...|:.|::.:...:.......:..|.|......|.:.:
plant   225 PRWLAKMGLTDDFETSLQVLRGFETDITVEVNEIKRSVASSSKRSAVRFVDLKRRRYYFPLMVGI 289

  Fly   329 GLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLAS 393
            ||:..||:.|||.|:||:|.||..|.. ..:..||..:|::|||||.::|.:|||.|||:||:.|
plant   290 GLLALQQLGGINGVLFYSSTIFESAGV-TSSNVATFGVGVVQVVATGIATWLVDKAGRRLLLMIS 353

  Fly   394 GISMAISTTAIGVYFFLQK---QDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATD 455
            .|.|.||...:.|.|:|::   .|:.....|..:.|..:...:|..|:|.||:|||:|.|:...:
plant   354 SIGMTISLVIVAVAFYLKEFVSPDSNMYNILSMVSVVGVVAMVISCSLGMGPIPWLIMSEILPVN 418

  Fly   456 IKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNE 520
            |||.|||:|...||.::::||.| .|:......||||.|:|.:....|:||...|||||||:|.|
plant   419 IKGLAGSIATLLNWFVSWLVTMT-ANMLLAWSSGGTFTLYALVCGFTVVFVSLWVPETKGKTLEE 482

  Fly   521 IQ 522
            ||
plant   483 IQ 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	129/363 (36%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	142/396 (36%)
AT1G19450	NP_173377.1	MFS_GLUT6_8_Class3_like	50..482	CDD:340916	158/442 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.820