DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and VGT1

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_186959.2	Gene:	VGT1 / 821117	AraportID:	AT3G03090	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	155/532 - (29%)
Similarity:	242/532 - (45%)	Gaps:	106/532 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 DQEN----LLGNMVHTSTS-------------NNSQKWPQYVAALAA-------AGGAFAAGTVL 101
            |.||    .:|.:|..|:|             |:|   |:..:.|||       |.||...|..:
plant     4 DPENQSISSVGQVVGDSSSGGITAEKEPLLKENHS---PENYSVLAAIPPFLFPALGALLFGYEI 65

  Fly   102 GWTSPA--------------------ETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIG 146
            |.||.|                    :..|:..|..|.        :.:||.:....|
plant    66 GATSCAIMSLKSPTLSGISWYDLSSVDVGIITSGSLYG--------ALIGSIVAFSVA------- 115

  Fly   147 FLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEI 211
               ::|||:..::.....:::|..:.:.|...|:|...|...|:..|.....||||..|.|..:|
plant   116 ---DIIGRRKELILAAFLYLVGAIVTVVAPVFSILIIGRVTYGMGIGLTMHAAPMYIAETAPSQI 177

  Fly   212 RGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICG-------IL--PLIFGAIFFFMPESPTYL 267
            ||.:.|..:....:|::..|.:|:    .|:::|.|       ||  |:|.|....::|.||.:|
plant   178 RGRMISLKEFSTVLGMVGGYGIGS----LWITVISGWRYMYATILPFPVIMGTGMCWLPASPRWL 238

  Fly   268 V-----SKDRSEN----AIKSIQWLRGKEY-DYEPE-----LAELRETDRETKANKVNVWAALNR 317
            :     .:...||    ||:|:..|||... |...|     ||||.....:.:|    .:..|.|
plant   239 LLRALQGQGNGENLQQAAIRSLCRLRGSVIADSAAEQVNEILAELSLVGEDKEA----TFGELFR 299

  Fly   318 PVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEA--NTGIEAEWATILIGIMQVVATFVSTLV 380
            ....|||.|:.||:.|||:.|..:|::||..|...|  :...:|...:||:|::::|.|.||.:|
plant   300 GKCLKALTIAGGLVLFQQITGQPSVLYYAPSILQTAGFSAAADATRISILLGLLKLVMTGVSVIV 364

  Fly   381 VDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPW 445
            :|::|||.|||.....|.||...:|.|:...|...|       :.||:|.|::..:.:.:||:.|
plant   365 IDRVGRRPLLLCGVSGMVISLFLLGSYYMFYKNVPA-------VAVAALLLYVGCYQLSFGPIGW 422

  Fly   446 LMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAV 510
            ||:.|:|...::|...|||...|:....:||..|..|.:.||.|..|..|..:.||.:.|:|:.|
plant   423 LMISEIFPLKLRGRGISLAVLVNFGANALVTFAFSPLKELLGAGILFCAFGVICVVSLFFIYYIV 487

  Fly   511 PETKGKSLNEIQ 522
            |||||.:|.||:
plant   488 PETKGLTLEEIE 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	110/382 (29%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	122/415 (29%)
VGT1	NP_186959.2	MFS_GLUT10_12_Class3_like	53..498	CDD:340920	140/477 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820