DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and INT1

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_850393.1	Gene:	INT1 / 818934	AraportID:	AT2G43330	Length:	509	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	146/494 - (29%)
Similarity:	227/494 - (45%)	Gaps:	50/494 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGE 116
            :|.....|..:.:..||              .|:..|....|  ..|.:.|:    :|.::....
plant    12 SGYLDMFPERRMSYFGN--------------SYILGLTVTAG--IGGLLFGY----DTGVISGAL 56

  Fly   117 GY---DFPVDKD----QFSWVGSAMT---LGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTM 171
            .|   ||.|.|.    |.:.|..|:.   :|||..    |::.:..|||...||..:.|..|..:
plant    57 LYIKDDFEVVKQSSFLQETIVSMALVGAMIGAAAG----GWINDYYGRKKATLFADVVFAAGAIV 117

  Fly   172 LIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAG 236
            :..|.:..:|.:.|.::|:..|...||||:|..|.:..|:||.|.|...||||.|....|.|.:.
plant   118 MAAAPDPYVLISGRLLVGLGVGVASVTAPVYIAEASPSEVRGGLVSTNVLMITGGQFLSYLVNSA 182

  Fly   237 VKIF-----WLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYD---YEPE 293
            ....     |:..:.|:..:|...:..||||||.:|..|:|...||:.:    .:.||   .|.|
plant   183 FTQVPGTWRWMLGVSGVPAVIQFILMLFMPESPRWLFMKNRKAEAIQVL----ARTYDISRLEDE 243

  Fly   294 LAELRETDRETKANK--VNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEA--N 354
            :..|...:.|.|..|  |...........|.|.....||..|||..|||.|::|:..|...|  :
plant   244 IDHLSAAEEEEKQRKRTVGYLDVFRSKELRLAFLAGAGLQAFQQFTGINTVMYYSPTIVQMAGFH 308

  Fly   355 TGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVV 419
            :...|.:.::::..|....|.|....:|..||:.|.|:|...:.||...:.|.||.|.:.::...
plant   309 SNQLALFLSLIVAAMNAAGTVVGIYFIDHCGRKKLALSSLFGVIISLLILSVSFFKQSETSSDGG 373

  Fly   420 SLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLND 484
            ..|||.|..|.|:|:.|:.|.|||||.:..|::....:|..|.::.|.||:...:|.:||:.:.:
plant   374 LYGWLAVLGLALYIVFFAPGMGPVPWTVNSEIYPQQYRGICGGMSATVNWISNLIVAQTFLTIAE 438

  Fly   485 GLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQ 523
            ..|.|.||.:.||:.|:.||||...||||:|.:.:|::|
plant   439 AAGTGMTFLILAGIAVLAVIFVIVFVPETQGLTFSEVEQ 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	115/378 (30%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	129/411 (31%)
INT1	NP_850393.1	Sugar_tr	34..479	CDD:278511	141/458 (31%)
INT1	NP_850393.1	MFS	35..464	CDD:119392	133/442 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810