DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a10

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001072926.1	Gene:	slc2a10 / 780388	XenbaseID:	XB-GENE-950490	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	497	Identity:	126/497 - (25%)
Similarity:	218/497 - (43%)	Gaps:	122/497 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 SAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILG----------WTMLIWAVNVSMLYASRF 186
            ||:..||....:..|.:|:..||:..:|...|..:.|          |.:::..|.:.      |
Frog    52 SAVLFGALLASLIGGIIIDRWGRRTAILASNLVVLAGSIILIATSTFWWLIVGRVTIG------F 110

  Fly   187 ILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG---AGVKIFWLSII-CG 247
            .:.|:..|.|:    |..||.:...||.|.|.::..||:|||..||:.   :||...|..:. ..
Frog   111 AISISSMACCI----YVSEIVRPHQRGMLVSLYETGITVGILISYAMNYFLSGVNESWKYMFGLA 171

  Fly   248 ILPLIFGAI-FFFMPESPTYL--VSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKV 309
            |:|..|..| ..|:|..|..|  ..:|..:..|:..:  .|:..:::|:..:.:.|..:...:|.
Frog   172 IVPAAFQFISILFLPSKPHKLNFWEQDTDDGFIELEE--TGEAGEFKPDTYDRQYTFLDLFRSKD 234

  Fly   310 NVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIF----LEANTGIEAEWATILIGIMQ 370
            |:         |....:.:||:.|||..|...|::|||.||    .::|:  .|..|::.:|:::
Frog   235 NM---------RTRTLLGLGLVLFQQFTGQPNVLYYASTIFQSVGFQSNS--SAVLASVGLGVVK 288

  Fly   371 VVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDA-------------------A 416
            |.:|.::....||.||||||||..|.|.|:.|.||:..|..|.|:                   :
Frog   289 VASTLIAICFADKAGRRILLLAGCIVMTIAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVS 353

  Fly   417 QVVS-----------------------------------------------------------LG 422
            |::.                                                           |.
Frog   354 QLLGIVHAETSTINTLDNSVHQLAMAIRSPSLANSASSNHKDLISQNSTVLPASPELPSNYTILN 418

  Fly   423 WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLG 487
            |:.:.|:..|:..||||:||:.|:::.|::..||:|.|.:...:.||....::|.||:::...:|
Frog   419 WITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIG 483

  Fly   488 IGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNR 529
            :..||.|:..:.::.:.|:||.:|||||:||.||.::.:..|
Frog   484 LSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEIDKQFSTKR 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	106/440 (24%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	114/474 (24%)
slc2a10	NP_001072926.1	MFS_GLUT10_Class3	10..517	CDD:340994	123/487 (25%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	250..256		3/5 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	528..555
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920