DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a11b

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_005165088.1	Gene:	slc2a11b / 564970	ZFINID:	ZDB-GENE-070705-96	Length:	522	Species:	Danio rerio

Alignment Length:	489	Identity:	136/489 - (27%)
Similarity:	218/489 - (44%)	Gaps:	81/489 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 AAAGGAFAAG---TVLGWTSPAETEIVDR--GEGYDFPVDKDQFS--W--VGSAMTLGAACVCIP 144
            |..||.|..|   :::...:.|....:::  .|.|...:..|..:  |  :.|..|:|.......
Zfish    50 AGIGGTFQYGYNISIINAPTKAVQNFINQTWTERYSTEISSDMLTLLWSIIVSIFTIGGLVGASV 114

  Fly   145 IGFLINMIGRKWTMLF-----LVLPFILGWTMLIWAVNVSMLYASRFILGI-AGGAFCVTAPMYT 203
            .|.|....|||.|:||     |:....:|  :...|....:|...||:.|: ||.|.|| .|:|.
Zfish   115 GGTLAIRFGRKGTLLFNNTFALLAALFMG--LSYPASTFELLVIGRFLTGVNAGIAICV-QPLYI 176

  Fly   204 GEIAQKEIRGTLGSFFQLMITIGILFVYAVG----AGVKIFW---LSIICGILPLIFGAIFF-FM 260
            ||||.:.:||.:.....:.||.|||....:|    .|...:|   ||.||  :|.:...:.. :.
Zfish   177 GEIAPRALRGAMAMGTSIFITGGILTGQVMGLKELLGKDEYWPILLSTIC--IPAVLQLLTLPWF 239

  Fly   261 PESPTYLVSKDRSENAI--KSIQWLRGKEYDYEPELAEL-RE----------------TDRETKA 306
            ||||.||:. ||.::..  |::.|..|:: .|..|:.:: ||                |||..:
Zfish   240 PESPRYLLI-DRGDDIACQKALMWFHGQD-KYHGEMEDIERERVSALGIKPKKPWELFTDRSIR- 301

  Fly   307 NKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGI---EAEWATILIGI 368
                 |..|...|...:          ||:.||||:.|||..:|.:|  ||   :..:||:..|.
Zfish   302 -----WQLLTLVVIHTS----------QQLNGINAIYFYADYVFTQA--GIPDDKIPYATVGTGA 349

  Fly   369 MQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASL-CL- 431
            .:.:......|:::.||||.|::.....|::......:  .|..||::.     |:|..|: |:
Zfish   350 CECITALTCGLLIESLGRRALIIGGYTLMSVCCICFTI--ALTFQDSSP-----WVPYLSMVCVL 407

  Fly   432 -FIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLF 495
             ||:.|.:|.|.|..::..|||....:..|..:.|:.||...||:...|..:.:||. ...|.:|
Zfish   408 AFILSFGLGPGGVTNILTTELFTQTDRPAAYMIGGSINWTSFFVIGMIFPFIVNGLK-QYCFLVF 471

  Fly   496 AGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNR 529
            ..:.::...:::|.|||||.|:..|||.|....:
Zfish   472 LVICLLVATYIFFVVPETKNKTFLEIQNEFKSRK 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	111/399 (28%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	118/432 (27%)
slc2a11b	XP_005165088.1	Sugar_tr	54..501	CDD:278511	133/479 (28%)
slc2a11b	XP_005165088.1	MFS	98..486	CDD:119392	116/420 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576863
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840