DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a5

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001008187.1	Gene:	slc2a5 / 493549	XenbaseID:	XB-GENE-494009	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	491	Identity:	153/491 - (31%)
Similarity:	245/491 - (49%)	Gaps:	57/491 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VAALAAAGGAFAAG-TVLGWTSPA--------ETEIVDRGEGYDFPVDKDQF-----SWVGSAMT 135
            |..:|..|.:|..| .|....||:        .|.|    |....|:: |.|     |...|...
Frog    24 VTLVATFGSSFQYGYNVASVNSPSPFMKDFYNSTNI----ERVGSPLE-DAFLTLLWSLTVSLYP 83

  Fly   136 LGAACVCIPIGFLINMIGRKWTML----FLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFC 196
            ||.....:.:|.|::.:|||.|:|    |.::|.||..|.:: |....::.|||..:|:..|...
Frog    84 LGGFFGSLLVGPLVSKLGRKGTLLFNNIFSIIPAILMGTSVV-AKTFEVIIASRLFVGVCAGLSS 147

  Fly   197 VTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG----AGVKIFW--LSIICGILPLIFGA 255
            ...|||.||::.|.:||.:|...|||||:|||.....|    .|....|  |..:.||..::..|
Frog   148 NVVPMYVGEMSPKNLRGAIGIMPQLMITVGILMAQIFGIRYILGNTEGWPILLALTGIPAVLELA 212

  Fly   256 IFFFMPESPTY-LVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKA-NKVNVWAALN-R 317
            ...|.||||.| |:.|...:.|.|::|.|||.| |.:.|:.|:.:.|:..|| .:::|..... |
Frog   213 FLPFFPESPRYTLLHKGNEDKAKKALQRLRGWE-DVDSEIKEMYQEDQSEKAEGQLSVRNLCTFR 276

  Fly   318 PVTRKALAI---SMGLMFFQQVCGINAVIFYASRIFLEANTGIEAE---WATILIGIMQVVATFV 376
            |:..:.::|   :||    ||:.|||||.:||..|:..|  |::.|   :.|:..|.:.|:.|..
Frog   277 PLRWQLISIIVMNMG----QQLSGINAVYYYADSIYKSA--GVKEETIQYVTVATGSVNVLMTLA 335

  Fly   377 STLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLP---VASLCLFIIMFSI 438
            :..:||..|||:|||:...:..||...:.:....|       .::.|:|   :|.:.:::|..:|
Frog   336 AVFIVDSWGRRVLLLSGFGTCCISCVVLTIALVYQ-------TTVSWMPYLSIACIIIYVIGHAI 393

  Fly   439 GYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGV 503
            |..|:|:::..|:|....:..|..:||:.:||..|::...|..|.:||| ...|.|||.:.:...
Frog   394 GPSPIPYVITTEMFRQASRPAAFMIAGSVHWLSNFIIGLIFEFLMNGLG-AYCFILFAAICLATF 457

  Fly   504 IFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK 539
            ||:|..|||||||:..|:.|.:|......:.:.:::
Frog   458 IFIYIVVPETKGKTFLEVSQLMAKRNGLEETVDSKE 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	119/383 (31%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	131/416 (31%)
slc2a5	NP_001008187.1	MFS_GLUT_Class2	24..475	CDD:340990	150/471 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R490
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940