DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_017175793.1	Gene:	Slc2a7 / 435818	MGIID:	3650865	Length:	553	Species:	Mus musculus

Alignment Length:	532	Identity:	149/532 - (28%)
Similarity:	253/532 - (47%)	Gaps:	78/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 LGNMVHTST---SNNSQKWPQYVAALAAAGGAFAAGT------------VLGWTSPAETEIVDRG 115
            :|...||..   :.:..:..:..:|||..|.|.||.|            :..|......:...:|
Mouse    23 IGEAQHTCAEYLNKDGGQRDRDTSALATLGSASAAHTSPDYPKCCLWLSLPVWLQHRRDQHTSQG 87

  Fly   116 --------------EGYDFPVDKDQ----FSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLF-- 160
                          |.:...:|:..    :|...|...||.....:.:|.::|..|||.|:|.
Mouse    88 GHKVLKSFYNDTHFERHGTFMDESTLLLLWSCTVSMFPLGGLLGSLVVGLMVNKWGRKGTLLINN 152

  Fly   161 ---LVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLM 222
               :....::|.:.:..|..:.:|  ||.::||..|....|.|||.||:|.:.:||.||:..::.
Mouse   153 VFAITSAVLMGVSKVARAFELIIL--SRVLVGICAGIAYSTLPMYLGELAPQNLRGALGTMTEVF 215

  Fly   223 ITIGILFVYAVGAGVKIFWLSIICG------IL------PLIFGAIFF-FMPESPTY-LVSKDRS 273
            :.||:|.       .:||.|..|.|      ||      |.:...:.. |.||||.| |:.|...
Mouse   216 VIIGVLL-------AQIFSLQAILGNATGWPILLALTGVPAVIQLLSLPFFPESPRYTLIEKGDE 273

  Fly   274 ENAIKSIQWLRGKEYDYEPELAELRETDRETKA-NKVNVWAALN----RPVTRKALAISMGLMFF 333
            |.|.::::.|||:.|:.|.|:.|:|..:|..:| .:::|   ||    ||:..:.::|.: ||..
Mouse   274 ETARQALRRLRGQNYNVEAEMEEMRTEERTEQAEGRLSV---LNLFTFRPLRWQLISIVV-LMAG 334

  Fly   334 QQVCGINAVIFYASRIFLEANTG-IEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISM 397
            ||:.|||||.:||..|:..|... .::::.|:..|::.:|.|.||.:::::|||||||| ||.::
Mouse   335 QQLSGINAVNYYADVIYTSAGVDPTQSQYVTLGSGVINLVMTLVSAVIIERLGRRILLL-SGYAI 398

  Fly   398 AISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGS 462
            ..|...:.....|.:..|.:   |.:|.:..:..:|:..|||..|||.::..|:.....:..|.:
Mouse   399 CCSACLVLTVALLLQSTAPE---LSYLSIVCVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFT 460

  Fly   463 LAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAG 527
            :.|..:||..|:|..||.::...:| ..:|.:|||:.::...::|..:|||||::..||....|.
Mouse   461 VDGAVHWLTNFIVGLTFPSIQVAIG-AYSFLVFAGVCILTAAYIYVVIPETKGRTFVEINCAFAK 524

  Fly   528 NRSTPQAIPAEK 539
            ....  ..|.||
Mouse   525 RNGV--EFPEEK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	114/385 (30%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	123/418 (29%)
Slc2a7	XP_017175793.1	MFS_GLUT_Class2	89..518	CDD:340990	130/446 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834127
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850