DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10960 and CG17930

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_650533.1	Gene:	CG17930 / 41979	FlyBaseID:	FBgn0038416	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	123/539 - (22%)
Similarity:	213/539 - (39%)	Gaps:	116/539 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 GSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQKWP-QYVAALAA------AGGAFA 96
            |.:|...|.    |||....|......  .::.|:.||:....| |..:..||      ||...|
  Fly    22 GPQQTTYIT----NGRQQQPPPPPPPT--TVIITTQSNSRWATPTQTQSGTAATLLFVYAGMDMA 80

  Fly    97 AGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSW-VGSAMTLGAACVCIPIGFL-----------I 149
            .|  |||...|.:     ....:|     |:|| :|  :.:||....|...||           :
  Fly    81 QG--LGWNLTAVS-----ANTLEF-----QYSWFIG--VIIGAVVSAITSAFLPKIVFYGLGGVM 131

  Fly   150 NMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGT 214
            |:|.   .::|:..|:           ....:.|:|::.|:..|...|...:::.|||....|||
  Fly   132 NLID---AIIFVSAPY-----------EYESILAARYVGGVGIGLITVPFLIHSAEIASSTNRGT 182

  Fly   215 LGSFFQLMITIGILF--VY----AVGAGVKIFWLSIICGILPLIFGAIFF----FMPESPTYLVS 269
            ..:..|..:.:|:..  :|    :.|.|:.|   :.:.||..::|.||..    ...:||.:.:.
  Fly   183 CCALEQYGLALGVAIQVIYDSQWSQGLGMTI---NRVHGIFGIVFTAIALGSVAITIDSPIFYIR 244

  Fly   270 KDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNVWAALNRPVTRKALAISM----GL 330
            :::.:.|..|::.|.|..:..|       ..||.....|:.|.....:.|..: |..||    .|
  Fly   245 QNQEQKARASVKQLMGSYWTRE-------AGDRAYDEAKLYVVEGSAQGVGEQ-LGESMMPFLKL 301

  Fly   331 MFFQQVCGI----NAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLL 391
            :.|:  |.:    :..:.|:.....|...|....|.||:.|:::::...::..|:|.:||:.:.|
  Fly   302 LLFR--CFVAFTFSVPLSYSILTTTELVEGTLHSWPTIIFGLLRLIGALITFAVLDTVGRKFVSL 364

  Fly   392 ASGISMA-ISTTAIGVY---------FFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWL 446
            ...:.|| :.....|||         :|:.     ||..|| :.......|.|..|..|
  Fly   365 LGLMCMAGLMLGMAGVYGDYGHIFDDYFMW-----QVCRLG-MAFQFFAGFFICSSSAY------ 417

  Fly   447 MMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAG-LTVVGVIFVYFAV 510
             :||.|...:|.|...|......::..:|...||...:   ...|:::..| :.|:|::.....:
  Fly   418 -LGEAFPMRVKPFLIGLIVCLEQVIHIIVIVKFVPTAE---FYYTYFVAVGIIMVIGLVAFAVLM 478

  Fly   511 PETKGKSLNEIQQELAGNR 529
            |||:|.:|.:     ||.|
  Fly   479 PETRGLTLRQ-----AGER 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	86/396 (22%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	93/430 (22%)
CG17930	NP_650533.1	Sugar_tr	102..493	CDD:278511	97/441 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444343
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740