Protein Alignment nebu and slc2a8

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_997963.1
• Gene: slc2a8 / 373140
• ZFINID: ZDB-GENE-030829-25
• Length: 498
• Species: Danio rerio
• Alignment Length: 516
• Identity: 181/516 - (35%)
• Similarity: 278/516 - (53%)
• Gaps: 45/516 - (8%)

  Fly    37 KYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVL 101
            :|...:|:.:    ::.||.....:|:..|..:         :....::|..||..|..:.|.||
Zfish     3 EYEENRPLLV----NDERTEEDRSEQDAYLDKV---------KNGKLFIATFAAVLGPLSFGFVL 54

  Fly   102 GWTSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFI 166
            |::|||..|: .|.:.....:..::.||.||.:|:|||...:..|:::..||||.:::|..:|||
Zfish    55 GYSSPAIPEL-RRIQDLRLQLSVEEASWFGSVVTIGAALGGLLGGWIVERIGRKLSLMFCAIPFI 118

  Fly   167 LGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVY 231
            .|:|.:|.|.|..|.|..|.:.|:|.|...:..|:|..|:|.:.:||||||..|||:.|||:..|
Zfish   119 FGFTTIIAAQNHWMFYVGRVLTGLASGVTSLVVPLYISEMAHERVRGTLGSCVQLMVVIGIMGAY 183

  Fly   232 AVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAE 296
            ..|..:...||::...|.|.:......||||:|.:|:.:.:...|..::::|||.:...|.|.|.
Zfish   184 VTGLFLDWRWLAVASSIPPTLMLLSMCFMPETPRFLLCQGKRREAEDALRFLRGPDAPAEWECAR 248

  Fly   297 LRETDRETKANKVNVWAA--LNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEA 359
            :.:..:    |:...::.  |..|...|.|.|.:.:|..||..||||::|||..||.:|:.. .:
Zfish   249 IEDAYK----NEEQSFSLGDLKDPGVYKPLGIGVMMMLLQQFTGINAIMFYAETIFEQAHFK-SS 308

  Fly   360 EWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYF---------------- 408
            :.||:::...|||.|.::.|::||.||::||:.||:.|.:|....||||
Zfish   309 DVATVIVAATQVVFTAIAALIMDKAGRKVLLILSGVVMCVSEAVFGVYFKLTVMKPNNSSMTSVL 373

  Fly   409 -----FLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSN 468
                 .|:.|.:|   .|.||.|.|:..||..|:||:||.|||:|.|:|.|.::|...:|...:|
Zfish   374 TDTHGLLEDQPSA---DLAWLAVGSMGFFIAGFAIGWGPTPWLVMSEIFPTRVRGLGSALCVLTN 435

  Fly   469 WLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNR 529
            |..||:|||||.||.|.|...||||:|:.|....|:|..|.|||||||:|.|||....|.|
Zfish   436 WTCAFIVTKTFQNLMDALSSAGTFWMFSALCASNVVFTAFFVPETKGKTLEEIQAGFKGTR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	165/443 (37%)
slc2a8	NP_997963.1	MFS_GLUT8_Class3	37..487	CDD:340991	170/458 (37%)