DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10960 and CG8837

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	474	Identity:	126/474 - (26%)
Similarity:	217/474 - (45%)	Gaps:	45/474 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PQYVAALAAAGGAFAAGTVLGWT-------SPAETEIVDRGE--GYDFPVDKDQFSWVGSAMTLG 137
            |:.|...|....|.|.|.:|.:.       :||...:.:..|  ..:...|....:|:...:.|.
  Fly     4 PKRVGGPAIQSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLS 68

  Fly   138 AACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMY 202
            ||...:..|||...||.|..:|...|..|.||..:.:..::..:||||...|:|.||..|..|::
  Fly    69 AALGALVSGFLALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIF 133

  Fly   203 TGEIAQ-KEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTY 266
            ..|||: :|....|....:|..|:|||..:.:|..|...:::|:...:..:|...|.|:.|||.|
  Fly   134 INEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGCAVSFVFTMTFPFVQESPHY 198

  Fly   267 LVSKDRSENAIKSIQWLRG-KEYD--YEPE-LAELRETDRETKANKVNVWAALNRPVTRKALAIS 327
            .:.|:...:..||::|.|| ::.|  .:|| |:||.|...|.::...||.:.   |::...:...
  Fly   199 YLRKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGST---PMSHGYIIRL 260

  Fly   328 MGLMFFQQVCGINAVIFYASRIFLEAN--------TGIEAEWATILIGIMQVVATFVSTLVVDKL 384
            ..:.|...||.      ..|.:|:|.|        ||...|...:::...|.....::.||..:|
  Fly   261 TFVSFLLTVCA------KLSGVFVELNYAADFLGRTGYSTETNYVVLASAQCAGALLARLVGPRL 319

  Fly   385 GRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLG-----WLPVASLCLFIIMFSIGYGPVP 444
            .|::||..|.:..|.:..|:.::     :....:..||     :||:..|.:.:.:.|.|..|:.
  Fly   320 PRKLLLCLSSLFAAAAVIALALF-----KAYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLA 379

  Fly   445 WLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTF--VNLNDGLGIGGTFWLFAGLTV-VGVIFV 506
            .::..|:..|.:.....|||...:|||.|.:.:.|  |......|:....|:|||.:: ||:|.:
  Fly   380 AVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISL 444

  Fly   507 YFAVPETKGKSLNEIQQEL 525
            .. :|||:.:..:.:|:||
  Fly   445 PL-LPETRNRRPSAVQREL 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	99/374 (26%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	110/410 (27%)
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	41/137 (30%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	112/409 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444278
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740