Protein Alignment nebu and SLC2A8

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_047279239.1
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 599
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 178/534 - (33%)
• Similarity: 275/534 - (51%)
• Gaps: 67/534 - (12%)

  Fly    35 GAKYGSRQPVKIVKASDNGRTSST-PHDQENLLGNMVHTSTSNNSQKWPQ--------------- 83
            |...|:.:|........:|..::| ||  |..:|.:...|..:.....|.
Human    91 GTGIGTLRPPPFPSGQASGPAATTFPH--ETGIGPLCPPSLPSGRASSPSAPTPPLGTSTGPLSP 153

  Fly    84 --YVAALAAAGGAFA---AGTVLGWTSPAETEIVDRGE-GYDFPVDKDQFSWVGSAMTLGAACVC 142
              ..:..|...|:|.   ||:  ||          ||. |..|.......:.:.:.:|||||...
Human   154 LPLPSGRARGPGSFTSEPAGS--GW----------RGRMGCGFGAPSSAAARLQAVVTLGAAAGG 206

  Fly   143 IPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIA 207
            :..|:|::..|||.::|...:||:.|:.::..|.:|.||...|.:.|:|.|...:.||:|..|||
Human   207 VLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIA 271

  Fly   208 QKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDR 272
            ...:||.|||..|||:.:|||..|..|..::..||:::..:.|.:...:..||||:|.:|:::.|
Human   272 YPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHR 336

  Fly   273 SENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVC 337
            .:.|:.::::|.|.|..:|         |....|.:....|.|.:|...|...|.:.||.|||:.
Human   337 RQEAMAALRFLWGSEQGWE---------DPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLS 392

  Fly   338 GINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTT 402
            |:|||:|||..||.||... ::..|::::|::||:.|.|:.|::|:.|||:||:.||:.|..||:
Human   393 GVNAVMFYAETIFEEAKFK-DSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTS 456

  Fly   403 AIGVYFFL-------------------QKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMM 448
            |.|.||.|                   |..||:  |.|.||.|.|:||||..|::|:||:|||:|
Human   457 AFGAYFKLTQGGPGNSSHVAISAPVSAQPVDAS--VGLAWLAVGSMCLFIAGFAVGWGPIPWLLM 519

  Fly   449 GELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPET 513
            .|:|...:||.|..:...:|||:||:|||.|.:|.:.|...|.|||.:...:..|:|..|.||||
Human   520 SEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPET 584

  Fly   514 KGKSLNEIQQELAG 527
            |||:|.:|.....|
Human   585 KGKTLEQITAHFEG 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	160/440 (36%)
SLC2A8	XP_047279239.1	PHA03307	3..>196	CDD:223039	22/118 (19%)
		MFS	36..591	CDD:475125	176/525 (34%)