DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and CG33281

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	469	Identity:	144/469 - (30%)
Similarity:	244/469 - (52%)	Gaps:	20/469 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 TSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDF-PVDKDQFSWVGSAMTLG 137
            :|....|: ||:||::....:.:.|...||.|.:..|:.......|. |:......||.|.:.||
  Fly     2 SSTGGDKY-QYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLG 65

  Fly   138 AACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMY 202
            .........:|.:.||||..::::.||.:|||.::.:|.....|..:|||.|.|||......|:|
  Fly    66 GLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIY 130

  Fly   203 TGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYL 267
            ..|:|...|||.||.|..|....|::..:.:|.......:|.|...|..:|...|:||||:|.:|
  Fly   131 IAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCFWFMPETPQHL 195

  Fly   268 VSKDRSENAIKSIQWLR------GKEY--DYEPELAELRETDRETKANKVN--------VWAALN 316
            ...::.|.|..|:::.|      .||.  :.:.||.:|:.|:: |.|:.|:        .|:...
  Fly   196 AKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEK-TTADGVDDDDAATGVTWSDFA 259

  Fly   317 RPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVV 381
            ...||||..|.:||:.|.|:||..|::.|.:.||.:|.:.:....|.|::|::|::.|:.||::|
  Fly   260 EGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLV 324

  Fly   382 DKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWL 446
            ::|||:||||.|.:.:.:..:|:|.|.:.|.. ...|.|..|:|:|.....:.:.::|...:|:|
  Fly   325 ERLGRKILLLVSAVGIGLGQSAMGTYSYFQML-GCPVASFSWVPIAGFSFMLFLAAVGLLSLPFL 388

  Fly   447 MMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVP 511
            ::.|:....|:..|..:..::.||::....|......:.||:.||.::||.|:.:..||:...||
  Fly   389 VVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVP 453

  Fly   512 ETKGKSLNEIQQEL 525
            ||||||::.|...|
  Fly   454 ETKGKSVDAILASL 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	113/373 (30%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	123/406 (30%)
CG33281	NP_995620.1	MFS	50..452	CDD:119392	121/403 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444284
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I1031
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	8	7.900