Protein Alignment nebu and Slc2a3

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001399481.1
• Gene: Slc2a3 / 25551
• RGDID: 3706
• Length: 495
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 153/487 - (31%)
• Similarity: 235/487 - (48%)
• Gaps: 54/487 - (11%)

  Fly    75 SNNSQKWPQYVAALAAAG-GAFAAGTVLGWTSPAETEIVD--------RGEGYDFPVDKDQFSWV 130
            ||.....|..|.|:..|. |:|..|...|..:..||.|.|        |.|  |.|.:
  Rat     3 SNKQNVTPSLVFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLE--DLPSE------- 58

  Fly   131 GSAMTLGAACVCI----------PIGFLINMIGRKWTMLFLVLPFILGWTMLIW---AVNVSMLY 182
            |...||.:.||.|          .:|..:|..||:.:||.:.|..|||..::.:   |.:|.||.
  Rat    59 GLLTTLWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLI 123

  Fly   183 ASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG----AGVKIFW-- 241
            ..|.|:||..|......|||.||::...:||..|:..||.|.:|||.....|    .|.:..|
  Rat   124 LGRLIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPG 188

  Fly   242 ---LSIICGILPLIFGAIFFFMPESPTY-LVSKDRSENAIKSIQWLRGKEYDYEPELAELR-ETD 301
               |:||..||.   .|...|.||||.: |:::...:.|.:.:|.|.|.. |...|:.|:: |:.
  Rat   189 LLGLTIIPAILQ---SAALPFCPESPRFLLINRKEEDQATEILQRLWGTP-DVIQEIQEMKDESI 249

  Fly   302 RETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGI-EAEWATIL 365
            |.::..:|.|......|...:.|.||:.|...||..|||||.:|::.||.:|  |: |..:|||.
  Rat   250 RMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDA--GVQEPIYATIG 312

  Fly   366 IGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLC 430
            .|::..:.|.||..:|::.|||.|.:.....||:.:..:.:...|:.:..|    :.::.:.::.
  Rat   313 AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEA----MSFVCIVAIL 373

  Fly   431 LFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLF 495
            :::..|.||.||:||.::.|||:...:..|.::||.|||...|:|...|.:....|| ...|.:|
  Rat   374 VYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLG-AYVFIIF 437

  Fly   496 AGLTVVGVIFVYFAVPETKGKSLNEIQQELAG 527
            |...|..:||.:|.||||||::..:|.:...|
  Rat   438 AAFLVFFLIFTFFKVPETKGRTFEDITRAFEG 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	142/453 (31%)
Slc2a3	NP_001399481.1	MFS_GLUT_Class1	14..458	CDD:340989	146/463 (32%)