Protein Alignment nebu and itr2

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_593320.1
• Gene: itr2 / 2541827
• PomBaseID: SPAC20G8.03
• Length: 557
• Species: Schizosaccharomyces pombe
• Alignment Length: 552
• Identity: 140/552 - (25%)
• Similarity: 248/552 - (44%)
• Gaps: 52/552 - (9%)

  Fly     1 MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQE-N 64
            ::|..||:..|::...:..:...|:..                 |:..:.|.....|.|:::| |
pombe     8 LATIKSSDDKGKDFIVEMTTRPSETKK-----------------KVPFSEDMREIPSLPNEEEAN 55

  Fly    65 LLGNMVHTSTSNN-----SQKWPQYVAALAAAGGAFAAGTVLGW-TSPAETEIVDRGEGYDFPVD 123
            ......:.....|     ::|...::..|:|..|  .:|.:.|: |......:...|......:.
pombe    56 ATDPQANEVADENGEGFEAEKISSWIWVLSAVAG--ISGLLFGYDTGVISGALAVLGSDLGHVLS 118

  Fly   124 KDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFIL 188
            ..|...:.||.:..|.......|:|.:.:|||..:|.....|::|..::..:.||:|:...|||:
pombe   119 SGQKELITSATSFAALISATTSGWLADWVGRKRLLLCADAIFVIGSVIMAASRNVAMMVVGRFIV 183

  Fly   189 GIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAG---VKIFWLSIICGI-- 248
            |...|...:..|||..|:|...:||.|...:.:.||.|.|..|::.|.   |...| .|:.||
pombe   184 GYGIGLTSLIVPMYITELAPARLRGRLVIIYVVFITGGQLIAYSLNAAFEHVHQGW-RIMFGIGA 247

  Fly   249 LPLIFGAI-FFFMPESPTYLVSKDRSENAIKSIQWL----RGKEYDYEPELAELRETDRETKANK 308
            .|.:...| .|:.||||.||:..:..|...|.:..:    :..|..|:..|.:........:.||
pombe   248 APALGQLISLFWTPESPRYLLRHNHVEKVYKILSRIHPEAKPAEIAYKVSLIQEGVKVDFPEGNK 312

  Fly   309 V-----NVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWA-TILIG 367
            .     ::......|..|::|.|...|.:|||..|.||:.::::.||  .:.|.:...: :|::|
pombe   313 FQHFFHSLKVLFTVPSNRRSLFIGCFLQWFQQFSGTNAIQYFSAIIF--QSVGFKNSISVSIVVG 375

  Fly   368 IMQVVATFVSTLVVDKLG-RRILLLASGISMA-ISTTAIGVYFFLQKQDAAQVVSLGW--LPVAS 428
            ....|.|.|:.:.:|::| |||||..|.:.:| ::..||..:|.  ..|..|..:.||  :.:||
pombe   376 ATNFVFTIVAFMFIDRIGRRRILLCTSAVMIAGLALCAIAYHFL--PADTTQNTNSGWQYVVLAS 438

  Fly   429 LCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFW 493
            :.:|:..::.|.|.:|| ...|||..:::......:...||:...:::.:|:.:.:.:...|||.
pombe   439 IIIFLASYASGIGNIPW-QQAELFPMEVRALGAGFSTAINWVGNLIISASFLTMMESITPTGTFA 502

  Fly   494 LFAGLTVVGVIFVYFAVPETKGKSLNEIQQEL 525
            ||||...||::..||..||..|.|:..|.:.|
pombe   503 LFAGFCFVGLVTSYFTYPELAGMSIENIHKLL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	121/441 (27%)
itr2	NP_593320.1	MFS_HMIT_like	87..521	CDD:340918	119/441 (27%)