DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and ght3

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_592790.1	Gene:	ght3 / 2541758	PomBaseID:	SPAC1F8.01	Length:	555	Species:	Schizosaccharomyces pombe

Alignment Length:	471	Identity:	112/471 - (23%)
Similarity:	213/471 - (45%)	Gaps:	61/471 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 GWTSPAETEIVDRGEGY-DF---------PVDK--DQFSWVGSAM--TLGAACVCIPIGFLIN-- 150
            ||...|:|..:....|. ||         |:..  ...:|..:.:  |:.|.|:   .|.:::
pombe    17 GWLQGADTGSISGILGMRDFQSRFADRYNPISNSYSYSAWRQALLTGTINAGCL---FGAMLSSP 78

  Fly   151 ---MIGRKWTMLFLVLPFILGWTMLIWAV-NVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEI 211
               .||:|:::.|....:|:...:|:.|| :...:...:.:.|:..||..|.:|.|..|:|..:|
pombe    79 FTERIGKKYSICFFSGVYIIAELLLVTAVPSWIQVLVGKILAGVGIGALSVLSPGYQSEVAPPQI 143

  Fly   212 RGTLGSFFQLMITIGILFVYAVGAGV-KI---------FWLSIICGILPLIFGAIFFFMPESPTY 266
            ||.:.:.:|:..|...|....:..|. |:         |.::::.||| |:.|.:  |:||||.|
pombe   144 RGAVVATYQIFSTGAALVAACINMGTHKLRKTASWRTSFGINMLWGIL-LMVGVL--FLPESPRY 205

  Fly   267 LVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNV--------WAALNRPVTRKA 323
            |:.|.|.|.|::    :.....:..|| :|:.:|:..|..:.:.:        |..:.....|..
pombe   206 LIYKGRDEEALR----IMCNMAELSPE-SEIIQTNFNTIKSDIEIEMAGGKARWIEIFGKDIRYR 265

  Fly   324 LAISMGLMFFQQVCGINAVIFYASRIFLEANTGI-EAEWATILIGIMQVVATFVSTLVVDKLGRR 387
            ..:...:|.|:::.|.|...:||:::|  ..||: :.....:::|.:....||.:...:|.||||
pombe   266 TCLGFLVMLFRELIGNNYYFYYATQVF--KGTGMTDIFLPAVILGAINFGTTFGALYTIDNLGRR 328

  Fly   388 ILLLASGISMAIS---TTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMG 449
            ..|:......:|.   ..|:|....:.|...:. ...|.:.:...|||:..:...:||:.|:::|
pombe   329 NPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSD-HRAGSVMIVFSCLFLFSYCCSWGPMGWVIVG 392

  Fly   450 ELFATDIKGFAGSLAGTSNWLLAFVVT--KTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPE 512
            |.|....:....|:|.:.|||..|:::  ..|:|...|..:|   :::|.:.:.....::|...|
pombe   393 ETFPIRYRSKCASVATSGNWLGNFMISFFTPFINNAIGFKLG---YIYACINLFSSFMIFFLAKE 454

  Fly   513 TKGKSLNEIQQELAGN 528
            |||.:|.|:......|
pombe   455 TKGLTLEEVNDLYMSN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	94/398 (24%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	99/433 (23%)
ght3	NP_592790.1	Sugar_tr	9..467	CDD:278511	111/466 (24%)
ght3	NP_592790.1	MFS	10..452	CDD:119392	105/451 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.710