DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and ght4

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_595064.1	Gene:	ght4 / 2539710	PomBaseID:	SPBC1683.08	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	469	Identity:	112/469 - (23%)
Similarity:	215/469 - (45%)	Gaps:	61/469 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 TVLGWTSPAETEIVDRGEGY-DF---------PVDK--DQFSWVGSAM--TLGAACVCIPIGFLI 149
            ::.||...|:|..:....|. ||         |:..  ...:|..:.:  |:.|.|:   .|.::
pombe    14 SMAGWLGGADTGSISGILGMRDFQSRFADRYNPITNSYSYSAWRQALLTGTVNAGCL---FGAML 75

  Fly   150 N-----MIGRKWTMLFLVLPFILGWTMLIWAV-NVSMLYASRFILGIAGGAFCVTAPMYTGEIAQ 208
            :     .||:|:::.|....:|:|..:|:.|| :...:...:...|:..||..|.:|.|..|:|.
pombe    76 SSPFTEAIGKKYSIAFFSGCYIIGQILLVTAVPSWVQIMVGKLFTGLTIGALSVLSPGYQSEVAP 140

  Fly   209 KEIRGTLGSFFQLMITIGILFVYAVGAGV-KI---------FWLSIICGILPLIFGAIFFFMPES 263
            .:|||.:.|.:||..|.|.|....:..|. |:         |.::|:.||. |:.|.:  |:|||
pombe   141 PQIRGAVVSTYQLFQTCGTLIAACINMGTHKLRKTASWRTSFGINILWGIF-LMVGVL--FLPES 202

  Fly   264 PTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNV--------WAALNRPVT 320
            |.||:.|.|.|.|::    :..:..:.:|| :|:.:|:..|..:.:.:        |..:.....
pombe   203 PRYLIYKGRDEEALR----IMCQTAELDPE-SEIIQTNFNTIKSDIEMEMAGGKARWPEVFGKEV 262

  Fly   321 RKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGI-EAEWATILIGIMQVVATFVSTLVVDKL 384
            |....:....|..:::.|.|...:||:::|  ..||: :.....:::|.:....||.:...:|.|
pombe   263 RYRTVLGFLTMLLRELIGNNYYFYYATQVF--KGTGMTDIFLPAVILGAINFGTTFGALYTIDNL 325

  Fly   385 GRRILLLASGISMAIS---TTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWL 446
            |||..|:......:|.   ..|:|....:.|...:. ...|.:.:...|||:..:...:||:.|:
pombe   326 GRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSD-HRAGAVMIVFSCLFLFSYCCSWGPMGWV 389

  Fly   447 MMGELFATDIKGFAGSLAGTSNWLLAFVVT--KTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFA 509
            ::||.|....:....::|.:.|||..|:|:  ..|::.:.|..:|   :::|.:.:.....::..
pombe   390 IVGETFPIRYRSKCAAVATSGNWLGNFMVSFFTPFISNSIGFKLG---YIYACINMTSAFQIFLM 451

  Fly   510 VPETKGKSLNEIQQ 523
            ..||||.:|.|:.:
pombe   452 AKETKGLTLEEVNE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	96/398 (24%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	101/433 (23%)
ght4	NP_595064.1	Sugar_tr	9..467	CDD:278511	112/469 (24%)
ght4	NP_595064.1	MFS	10..440	CDD:119392	106/442 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.710