Protein Alignment nebu and Slc2a1

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_620182.1
• Gene: Slc2a1 / 24778
• RGDID: 3704
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 147/490 - (30%)
• Similarity: 230/490 - (46%)
• Gaps: 60/490 - (12%)

  Fly    88 LAAAGGAFAAGTVLGWTS---PAETEIVDR----------GEGYDFPVDKDQFSWVGSAMTLGAA 139
            :.|.|||.......|:.:   .|..::::.          ||..........:|...:..::|..
  Rat    13 MLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGESIPSTTLTTLWSLSVAIFSVGGM 77

  Fly   140 CVCIPIGFLINMIGRKWTMLFL-VLPFI----LGWTMLIWAVNVSMLYASRFILGIAGGAFCVTA 199
            .....:|..:|..||:.:||.: :|.|:    :|::.|  ..:..||...|||:|:..|......
  Rat    78 IGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKL--GKSFEMLILGRFIIGVYCGLTTGFV 140

  Fly   200 PMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICG---ILPLIFGAIFF--- 258
            |||.||::...:||.||:..||.|.:|||.       .::|.|..|.|   :.||:...||.
  Rat   141 PMYVGEVSPTALRGALGTLHQLGIVVGILI-------AQVFGLDSIMGNADLWPLLLSVIFIPAL 198

  Fly   259 -------FMPESPTYLVSKDRSENAIKSI-QWLRGKEYDYEPELAELRETDRE-TKANKVNVWAA 314
                   |.||||.:|:.....||..||: :.|||.. |...:|.|::|..|: .:..||.:...
  Rat   199 LQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTA-DVTRDLQEMKEEGRQMMREKKVTILEL 262

  Fly   315 LNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAE-WATILIGIMQVVATFVST 378
            ...|..|:.:.|::.|...||:.|||||.:|::.||.:|  |::.. :|||..||:....|.||.
  Rat   263 FRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKA--GVQQPVYATIGSGIVNTAFTVVSL 325

  Fly   379 LVVDKLGRRILLLASGISMA----ISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIG 439
            .||::.|||.|.|.....||    :.|.|:.:        ..|:..:.:|.:.::..|:..|.:|
  Rat   326 FVVERAGRRTLHLIGLAGMAGCAVLMTIALAL--------LEQLPWMSYLSIVAIFGFVAFFEVG 382

  Fly   440 YGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVI 504
            .||:||.::.|||:...:..|.::||.|||...|:|...|..:....| ...|.:|..|.|:..|
  Rat   383 PGPIPWFIVAELFSQGPRPAAVAVAGFSNWTSNFIVGMCFQYVEQLCG-PYVFIIFTVLLVLFFI 446

  Fly   505 FVYFAVPETKGKSLNEIQQEL-AGNRSTPQAIPAE 538
            |.||.||||||::.:||.... .|..|.....|.|
  Rat   447 FTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	137/458 (30%)
Slc2a1	NP_620182.1	MFS_GLUT_Class1	14..458	CDD:340989	140/464 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	468..492		4/14 (29%)