Protein Alignment nebu and Slc2a2

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_112474.2
• Gene: Slc2a2 / 20526
• MGIID: 1095438
• Length: 523
• Species: Mus musculus
• Alignment Length: 519
• Identity: 158/519 - (30%)
• Similarity: 228/519 - (43%)
• Gaps: 90/519 - (17%)

  Fly    39 GSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVLGW 103
            |:..|:.:..|    .|:..|.|:|...|: .|..|    ..|...|::.|.  |...|....||
Mouse    63 GTDTPLTVTPA----YTTPAPWDEEETEGS-AHIVT----MLWSLSVSSFAV--GGMVASFFGGW 116

  Fly   104 TSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILG 168
            ..                 ||     :|....:.||          |.:.....:|.....|...
Mouse   117 LG-----------------DK-----LGRIKAMLAA----------NSLSLTGALLMGCSKFGPA 149

  Fly   169 WTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAV 233
            ..::|...:||.||.     |:..|    ..|||.||||...:||.||:..||.:..|||.....
Mouse   150 HALIIAGRSVSGLYC-----GLISG----LVPMYIGEIAPTTLRGALGTLHQLALVTGILISQIA 205

  Fly   234 G----AGVKIFW-----LSIICGILPLIFGAIFFFMPESPTYLVSKDRSE-NAIKSIQWLRGKEY 288
            |    .|.:..|     ||.:..:|..:   :..|.||||.||..|...| .|.||::.|||.|
Mouse   206 GLSFILGNQDHWHILLGLSAVPALLQCL---LLLFCPESPRYLYIKLEEEVRAKKSLKRLRGTE- 266

  Fly   289 DYEPELAELR----ETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRI 349
            |...::.|::    |...|.|.:.:.::...|   .|:.:.:::.|...||..|||.:.:|::.|
Mouse   267 DVTKDINEMKKEKEEASTEQKVSVIQLFTDAN---YRQPILVALMLHMAQQFSGINGIFYYSTSI 328

  Fly   350 FLEANTGI-EAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ 413
            |..|  || :..:|||.:|.:.::.|.||.|:|:|.|||.|.|...|.|...|..:.|...|..:
Mouse   329 FQTA--GISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLDK 391

  Fly   414 DAAQVVSLGWLPVASLC---LFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVV 475
            .|       |:...|:.   ||:..|.||.||:||.|:.|.|:...:..|.:||..|||:..||:
Mouse   392 FA-------WMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVI 449

  Fly   476 TKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK 539
            ...|..:.|.|| ...|:||||:.:|..:|.:|.||||||||..||..|.   |....:.|..|
Mouse   450 ALCFQYIADFLG-PYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEF---RKKSGSAPPRK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	137/438 (31%)
Slc2a2	NP_112474.2	MFS_GLUT_Class1	12..489	CDD:340989	149/494 (30%)