DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and K08F9.1

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_506734.2	Gene:	K08F9.1 / 187167	WormBaseID:	WBGene00010684	Length:	490	Species:	Caenorhabditis elegans

Alignment Length:	486	Identity:	126/486 - (25%)
Similarity:	220/486 - (45%)	Gaps:	72/486 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VAALAAAGGAFAAGTVLGWTSPAETEIVD--------RGEG--YDFPVDKDQFSWVGSAMTLGAA 139
            ||.:.:..|:|..|..|..|:|::...:.        |.:|  .|..: ::.:|:|.:.:.|||.
Worm    12 VAVITSMAGSFHYGYNLVLTNPSQDAFLSFMNQTFAKRFDGGLSDHTL-QNIWSFVVAVLFLGAL 75

  Fly   140 CVCIPIGFLINMIGRKWTMLFLV---------------LP----FILGWTMLIWAVNVSMLYASR 185
            .....|.|:...:|||..:...:               :|    :|:...::.|:|:||
Worm    76 AGSFSIPFIAEGVGRKNGLYISISVGVLAGGMSIASKFIPLFELYIISRVVMGWSVSVS------ 134

  Fly   186 FILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIF-----WLSII 245
              ||::|        ::..|.:.|:.||.:|......|.:|.: |.:|.|..:||     |..|.
Worm   135 --LGLSG--------IFLSEASPKQNRGAIGMMTGTAIQLGTV-VGSVVAMPQIFGTDDLWWVIY 188

  Fly   246 C---GILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAE--LRETDRE-- 303
            .   ||: |:|||...|.||||.||:.|...|:|..||.:.    |..|.|.|:  ::|..:|
Worm   189 ATEIGIM-LVFGAALPFFPESPGYLIQKGSLESATISISFY----YKCEKEEADKHVKEIQKEQM 248

  Fly   304 TKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTG---IEAEWATIL 365
            ....|..:...:.:...|....:...:.|.....|:..:..:|..|.:  |||   ::|..|...
Worm   249 NSTKKFTMLDVIQQKSLRDKAFVGAVVTFVMSFSGVAVISAFAFEILV--NTGLNVLQASLANDA 311

  Fly   366 IGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLC 430
            ..|:.|:::.::..::||.|||.|||.|...:.|....|....|...:...||  ||::.:..:|
Worm   312 TTIVSVISSVLAIAIIDKNGRRPLLLISLAGILICNLIIFGLMFTFDKFGNQV--LGFILIFFIC 374

  Fly   431 LFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFW-L 494
            :|...|::|.||:.:.:..||...|.:..|.|.|.....:..|.:...|:.:.:.||...::. |
Worm   375 IFQFFFALGPGPLSYFINAELVGQDARSAAQSWASVVQMISQFSIITAFLPMKNQLGEAWSYLIL 439

  Fly   495 FAGLTVVGVIFVYFAVPETKGKSLNEIQQEL 525
            |.....|.::|:||::||||.||..|:::.:
Worm   440 FVAPVAVSLVFLYFSLPETKNKSPIEVEEAI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	100/392 (26%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	107/424 (25%)
K08F9.1	NP_506734.2	MFS	13..461	CDD:391944	122/474 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850