DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and F48E3.2

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_509266.1	Gene:	F48E3.2 / 185981	WormBaseID:	WBGene00018603	Length:	488	Species:	Caenorhabditis elegans

Alignment Length:	469	Identity:	102/469 - (21%)
Similarity:	199/469 - (42%)	Gaps:	85/469 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 FPVDKDQFSWVGSAMT----LGAACVCIPIGFLINMIGRKWTM-----------------LFLVL 163
            :.:...:|.|..|||.    :|.|...:....:.:.||||||:                 :.|.:
Worm    49 YTLSNSEFEWAWSAMLAIYFIGFAAGSVISAGVADRIGRKWTLFLGTCGSLLSSLIALFAIILKM 113

  Fly   164 PFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAP-------MYTGEIAQKEIRGTLGSFFQL 221
            |.:.|::.|:.:::.::......:|      |..::|       .:..|:| ..|...:|..|.:
Worm   114 PLMFGFSRLVMSLSAAISMNGLILL------FQESSPSHMRGLISFNAEMA-FVITNLIGGLFGM 171

  Fly   222 MITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYL-VSKDRSENAIKSIQWLRG 285
            ...:|...|..:  .|.|...|:.|        .:..|:.|||.|| :.|..:..|.:::|:.:.
Worm   172 QSILGQNIVGLI--AVSIIPSSVAC--------FLTVFLKESPKYLFLKKHDATEAGRALQFYQN 226

  Fly   286 KEYDYEPEL-------AELRETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVI 343
            .: |.|.::       .|..|...:...:..::.|  |:||.|..|   :||...|....:..|:
Worm   227 IK-DEEEKMNVLNDLKLEKEEMGHQKNGSLFDIMA--NQPVRRGFL---LGLATMQLTASVWPVV 285

  Fly   344 FYASRIFLEANTGIE-AEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVY 407
            ||::...::|....| :|..:..:..:..::|.|...:|:|..|:.||:.:.   :::..||.|:
Worm   286 FYSTDFLMDAGFSYELSESVSTGMLFLSSLSTIVGMFIVEKYSRKWLLIGTA---SVNIAAILVF 347

  Fly   408 FFLQKQDAAQVVSLGWLPV---ASLCLFI--IMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTS 467
                  ..:.::|..|..:   ..:||.:  |.:|:..||:.|.:..||...:.:..:.||....
Worm   348 ------SLSAILSHYWTWIGYGCIICLILHGISYSVAMGPIAWFITSELVPINFRAASQSLVLAL 406

  Fly   468 NWLLAFVVTKTFVNLNDGLGIGG----TFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQEL--- 525
            |..:|.|:  .|:.......||.    .|::..|:..:.::.:|  :||||.|.:|.|.::|
Worm   407 NHTVALVL--AFLTFPLYKTIGPITLVIFFVIPGILCIIMLILY--LPETKDKHINVIVEQLRET 467

  Fly   526 AGNRSTPQAIPAEK 539
            ...|...|.:..|:
Worm   468 KAKRKESQKLETEE 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	84/395 (21%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	90/433 (21%)
F48E3.2	NP_509266.1	MFS_GLUT_Class1_2_like	12..455	CDD:340915	95/441 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52445
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930