Protein Alignment nebu and hmit-1.2

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_507624.1
• Gene: hmit-1.2 / 180206
• WormBaseID: WBGene00013074
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 151/619 - (24%)
• Similarity: 243/619 - (39%)
• Gaps: 163/619 - (26%)

  Fly    48 KASDNGRTSSTPHDQEN-LLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEI 111
            |.|::||    |..::| .||..|             |:...||..|.|..|        .:|.:
 Worm     7 KVSESGR----PRPEKNPKLGFFV-------------YLLGSAAIIGGFLFG--------YDTSV 46

  Fly   112 VDRGEGY--DFPVDKDQFS-W--VGSAMTLGAACVCIPI-GFLINMIGRKWTMLFLVLPFILG-- 168
            |.....|  :.|..|...: |  |..::|.|.|.|.... |...:..|||..::...|.|:.|
 Worm    47 VSAAMLYVPEAPGLKPMGTVWKEVIVSITPGMAAVGAWFSGAGSDRYGRKPIIIGSTLIFVCGAV 111

  Fly   169 -----WTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGIL 228
                 ||.::..:       .|..||:..|...:..|:|.||.:...:||||.|.|.:||:.|.:
 Worm   112 ICAVAWTKIVMLI-------GRIFLGVGIGFASMVVPVYLGEASPTHVRGTLVSAFAMMISFGQV 169

  Fly   229 FVYAVGAGVKIFW---------LSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLR 284
            ....:| ||..:|         :....||..||....|.|:||:|.:|.....:|.|.:.::.:.
 Worm   170 VANIMG-GVFSYWEPYTIGWRLMFAFAGIPALIQFVCFIFLPETPRWLYENGHTEQAEQVLEKIY 233

  Fly   285 GKEYDY-EPELAEL--------RETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGIN 340
            |...:: |.||||:        ::.:.|.|:..| :|..|..|...||..|...|..|||:.|||
 Worm   234 GGNTEWIEYELAEIKTYAEERQKQMEEEKKSGPV-IWRILKTPHVLKACFIGSMLQAFQQLAGIN 297

  Fly   341 AVIFYASRIFLEANTGIE----AEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAIST 401
            .:::|.:.|...|  |||    ..|.::::.|..::..|.....::|||||.|.|.|...:.:|.
 Worm   298 TILYYTADIIRSA--GIENYHTIIWISVILSICNLIGPFAPMFFIEKLGRRKLFLFSCAGVVVSL 360

  Fly   402 TAIGVYFFLQKQDAA-------------------------------------------------- 416
            ..|||.|.|...|:|
 Worm   361 VLIGVSFLLVGNDSAPNFDRSAYLLAGNYQSNGEAESCLMLSNCDSCVTSEHCGFCEDSETRTGF 425

  Fly   417 ------------------------------QVVSLGW-----------LPVASLCLFIIMFSIGY 440
                                          ...|..|           ||:..:.::::.||.|:
 Worm   426 CLPVDHNDVTLYSSTGLCTNGLDKSNSSFPNATSYVWQKHHCTTSYTILPIVMMGVYLLTFSCGF 490

  Fly   441 GPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIF 505
            ..:||::..|.:....:....|::..|||:...::..|:::|...:...|.|||:|..|::..||
 Worm   491 TSLPWVLNSEFYPMWARSTCVSISTLSNWVFNLIIALTYLSLTHAITKYGAFWLYAIFTIIAFIF 555

  Fly   506 VYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK 539
            :||.||||.|.|::|::......|....|:.|.:
 Worm   556 IYFLVPETTGYSIDEVEMLFMNKRQRNIAMQARQ 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	132/546 (24%)
hmit-1.2	NP_507624.1	MFS	32..562	CDD:475125	132/548 (24%)