Protein Alignment CG10960 and hmit-1.1

DIOPT Version :9

• Sequence 1: NP_648605.1
• Gene: CG10960 / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 144/593 - (24%)
• Similarity: 237/593 - (39%)
• Gaps: 163/593 - (27%)

  Fly    85 VAALAAAG----------GAF-----AAGTVLGWTSPAETEIVDRGEGY--DFPVDKDQFS-W-- 129
            |||.:::|          |.|     ||..:.|:....:|.:|.....|  |.|..|...: |
 Worm     4 VAAFSSSGQDKPAHTPKLGLFVYILAAASVIGGFLFGYDTSVVSAAMLYMPDAPGLKPMDTVWQE 68

  Fly   130 -----------VGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYA 183
                       |||.|:          |...:.|||:..:|.....|.:|..:...:||..||..
 Worm    69 VLVSISPGMAAVGSLMS----------GTSSDYIGRRKVILGASAIFTIGALVCAASVNKIMLLV 123

  Fly   184 SRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAG------VKIFW- 241
            .|.:||||.|...:..|:|.||.|...:||.|.:.|.|||:.|.:.....|..      ..:.|
 Worm   124 GRVLLGIAIGFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVGWR 188

  Fly   242 LSIICGILPLIFGAI-FFFMPESPTYLVS---KDRSENAIKSI-----QWLRGKEYDYEPELAEL 297
            |......:|.|...: |.|:||:|.:|..   :..:...::.:     :|:   ||    |:||:
 Worm   189 LMFAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLEKVYNGDKEWV---EY----EMAEI 246

  Fly   298 --------RETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEAN 354
                    :|.::...:..| :|..|..|...||..|...|..|||:.|||.:::|.:.|.  .:
 Worm   247 IAFNEDQAKENEKAHASGPV-IWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADII--RS 308

  Fly   355 TGIEAE----WATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDA 415
            :||...    |.::|:.:...:..||...:::|:||||:.|.|...:.:|...|||.|.|...|:
 Worm   309 SGISNNHTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDS 373

  Fly   416 AQVV-----------------------------------------------------------SL 421
            |..:                                                           |.
 Worm   374 AATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSST 438

  Fly   422 G--------------W-----------LPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAG 461
            |              |           ||:.:..::::.||.|:..:||::..|.:....:....
 Worm   439 GSCTNSNGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCV 503

  Fly   462 SLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELA 526
            :::.||||:...::..|:::|...:|..|.|||:|||||:..||:.|.||||||.|:.|::....
 Worm   504 AISTTSNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEVEMLFM 568

  Fly   527 GNRSTPQA 534
            ..:...:|
 Worm   569 NKKQRREA 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	109/484 (23%)
		MFS	118..508	CDD:119392	123/517 (24%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	129/542 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I2130
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.870