DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and R09B5.11

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_503413.2	Gene:	R09B5.11 / 178634	WormBaseID:	WBGene00019979	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	532	Identity:	157/532 - (29%)
Similarity:	244/532 - (45%)	Gaps:	79/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQ-----KWPQYV------AALAAAGGAFAAG-- 98
            |.||.|....|..:.:.....|:..:...|:.|     .|..::      .|||:....|..|
Worm     4 VVASQNKNDRSFSNMESESSSNVEKSEKENHHQSLPDENWTPFLFFCISSIALASFQDGFQIGCI 68

  Fly    99 -----TVLGWTSPAETEIVDRGE-------GYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINM 151
                 .::.|......|:.  ||       .:.:.|....|| ||.  ..|:.|    .|||.:.
Worm    69 NAPGPLIIDWIKKCHFELF--GEVLSQYQADFIWSVAVSMFS-VGG--MFGSFC----SGFLADK 124

  Fly   152 IGRKWTMLFLVLPFILGWTMLIWAVNVS---------MLYASRFILGIAGGAFCVTAPMYTGEIA 207
            .|||.|:|:..:      ..|:.||.:|         |:...||::|:..|......||:..|:|
Worm   125 FGRKSTLLYNNI------LALLAAVCLSTSKLFNFYPMIVFGRFLVGLNCGITSGLVPMFLTELA 183

  Fly   208 QKEIRGTLGSFFQLMITIGILFVYAVGA----GVKIFWLSII-CGILPLIFG-AIFFFMPESPTY 266
            ...:||..|||.||.|::.|:...|:|.    |.::.|..|. |..:|.... |...|..|||.|
Worm   184 PANLRGKCGSFHQLNISVAIVLSQALGLPQIFGTQVGWPYIFACVAIPTFLQLATIPFCVESPKY 248

  Fly   267 LVSK--DRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNV-------WAALNRPVTRK 322
            |:||  || |.|.:.::.|||.....|    ||....:||   .|.|       :.:|.:...:.
Worm   249 LISKLNDR-EEARRILEKLRGHTKVDE----ELEHMVQET---MVTVEPLHQPGYVSLFKGDNQW 305

  Fly   323 ALAISMGLMFFQQVCGINAVIFYASRIFLEAN-TGIEAEWATILIGIMQVVATFVSTLVVD--KL 384
            .:.:|:.:||.||..||:||.||::.||.... :|.|..:||:..|.::::|||....::|  |.
Worm   306 PMIVSILMMFSQQFSGISAVTFYSTLIFKRNGLSGNEPMYATVGFGCIKLIATFGCLFLIDHPKF 370

  Fly   385 GRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMG 449
            ||:.|.:|....|.||:..|.:...|..   |......::.|..:..|::.|:.|.||:||....
Worm   371 GRKRLHIAGLSGMCISSILIVITLTLSN---AGYHWASYMNVLFILSFVVTFAFGPGPIPWFFTS 432

  Fly   450 ELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETK 514
            |||.:..:|.|.:::.||||:..::|..||:.:|:.:. ...|.:|...|....||.:..|||||
Worm   433 ELFDSATRGRAAAVSATSNWVANWMVGLTFLPINNIIH-QYAFLMFTFFTFTFAIFTWKFVPETK 496

  Fly   515 GKSLNEIQQELA 526
            |||.:.|::|||
Worm   497 GKSPSAIRKELA 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	118/383 (31%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	127/416 (31%)
R09B5.11	NP_503413.2	Sugar_tr	54..499	CDD:278511	142/471 (30%)
R09B5.11	NP_503413.2	MFS	90..465	CDD:119392	121/398 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810