Protein Alignment nebu and hmit-1.3

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 153/602 - (25%)
• Similarity: 243/602 - (40%)
• Gaps: 161/602 - (26%)

  Fly    43 PVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPA 107
            ||.....|...|.||.|                  ...|..|:.|.:|..|.|..|...|..|.|
 Worm     6 PVAAGAGSGQTRPSSDP------------------KTGWFVYMLAFSAVIGGFLFGYDTGIVSAA 52

  Fly   108 ETEIVDRGEGYDFPVDKDQFSW--VGSAMTLGAACV---CIPIGFLINMIGRKWTMLFLVLPFIL 167
            .. .|....|.. |:|.   .|  :..::|.|.|.:   |...|  .:.:|||..::...:.|.:
 Worm    53 ML-YVPNASGIK-PLDS---VWQEIIVSITPGVAAIGSLCSGPG--SDFLGRKKIIIGASVTFTI 110

  Fly   168 G-------WTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITI 225
            |       ||.:|       |...|.:||:|.|...:..|:|..|.:...|||.|.:.||||||:
 Worm   111 GAIICAAAWTKII-------LLIGRILLGLAIGFASMIVPIYVSEASPSHIRGKLVTGFQLMITV 168

  Fly   226 GILFVYAVGAGV------KIFW-LSIICGILPLIFGAI-FFFMPESPTYLVSKDRSENAIKSI-- 280
            |::....:|...      ::.| |......:|.|...: |.|:||||.:|....|:..|.:.:
 Worm   169 GLVIANIIGGAFSYVDPDQVGWRLMFAFAAVPAIIQFVCFLFLPESPRWLYEHGRTVEAREVLTR 233

  Fly   281 ------QWLRGKEYDYE-PELAELRETDRETKA----NKVNVWAALNRPVTRKALAISMGLMFFQ 334
                  :|:     ||| .|::...|.:...||    |...:...|..|..|||:.|...|..||
 Worm   234 IYNGHTEWV-----DYEINEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQ 293

  Fly   335 QVCGINAVIFYASRIFLEANTGIEAEWATILIGI----MQVVATFVSTLVVDKLGRRILLLASGI 395
            |:.|||.|::|...|...|  |::....||.|.:    :..:.||:...:|:::|||:|||.|.|
 Worm   294 QLSGINTVMYYTGNIIRSA--GVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMI 356

  Fly   396 SMAISTTAIGVYFFLQKQDA------------------------------------------AQV 418
            .:.:...|:||.|.|...|:                                          ::|
 Worm   357 GVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGFCESKV 421

  Fly   419 VSLGW-------------------------------------------LPVASLCLFIIMFSIGY 440
            ...|:                                           ||:..:..:::.||.||
 Worm   422 AKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTDFEWEDTYCHTKFTVLPIIIMVFYLLSFSAGY 486

  Fly   441 GPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIF 505
            .|:||::..|.:....:..|.|::...||:...:|:.||::|:......|||:::.|.|:|.::|
 Worm   487 APLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVF 551

  Fly   506 VYFAVPETKGKSLNEIQ 522
            |:|.||||||.|::|::
 Worm   552 VFFFVPETKGYSIDEVE 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	138/542 (25%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:475125	136/544 (25%)
		MFS	<190..>249	CDD:475125	17/63 (27%)