Protein Alignment nebu and fdgt-1

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_493982.1
• Gene: fdgt-1 / 173525
• WormBaseID: WBGene00019207
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 145/545 - (26%)
• Similarity: 254/545 - (46%)
• Gaps: 76/545 - (13%)

  Fly    15 NKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTST---SN 76
            ::||.|:...::.|.:|:::.:.|           |..|.|:......:..|...:..|.   :.
 Worm     2 SEKSRSDTSATASLSDSSKSPSSY-----------STPGTTTQKIIFPDGKLTKCLAFSAFVITL 55

  Fly    77 NSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSW--VGSAMTLGAA 139
            .|.::..::..:.|.|     |.:..|...:..::.|:    :...:....:|  ..|...:|..
 Worm    56 ASFQFGYHIGCVNAPG-----GLITEWIIGSHKDLFDK----ELSRENADLAWSVAVSVFAVGGM 111

  Fly   140 CVCIPIGFLINMIGRKWTMLF-----LVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTA 199
            ...:..|:|.:.:||:..:.:     |....::|....:.|  ..|:...|.|:|:..|......
 Worm   112 IGGLSSGWLADKVGRRGALFYNNLLALAAAALMGLAKSVGA--YPMVILGRLIIGLNCGFSSALV 174

  Fly   200 PMYTGEIAQKEIRGTLGSFFQLMITIGIL------FVYAVGAGVK---IFWLSIICGILPLIFGA 255
            ||:..||:...:||.|||..||::||.||      ..:.:|.|.:   ||..:::..:|.|   |
 Worm   175 PMFLTEISPNNLRGMLGSLHQLLVTIAILVSQIFGLPHLLGTGDRWPLIFAFTVVPAVLQL---A 236

  Fly   256 IFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETD---RETKANKVNVWAA--L 315
            :....||||.|.::             :||:..:.|..|.:||:|:   .|.:|.:....||  .
 Worm   237 LLMLCPESPKYTMA-------------VRGQRNEAESALKKLRDTEDVSTEIEAMQEEATAAGVQ 288

  Fly   316 NRP----VTRKAL----AISMGLMFFQQVCGINAVIFYASRIFLEAN-TGIEAEWATILIGIMQV 371
            .:|    :.:.||    :|::.:|..||:.|||..:||::.||..|. ||.|..:|||.:|.:.|
 Worm   289 EKPKMGDMFKGALLWPMSIAIMMMLAQQLSGINVAMFYSTVIFRGAGLTGNEPFYATIGMGAVNV 353

  Fly   372 VATFVSTLVVD--KLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFII 434
            :.|.:|..:||  |.|||.||||....|.:||..:.....:|.....:..|  :..:..:.||:|
 Worm   354 IMTLISVWLVDHPKFGRRSLLLAGLTGMFVSTLLLVGALTIQNSGGDKWAS--YSAIGFVLLFVI 416

  Fly   435 MFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLT 499
            .|:.|.|.:||..:.|:|.:..:|.|.|:|...||....:|..||:.:|: |....:|::|:|..
 Worm   417 SFATGPGAIPWFFVSEIFDSSARGNANSIAVMVNWAANLLVGLTFLPINN-LMQQYSFFIFSGFL 480

  Fly   500 VVGVIFVYFAVPETKGKSLNEIQQE 524
            ...:.:.:..||||||||:.:||.|
 Worm   481 AFFIFYTWKFVPETKGKSIEQIQAE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	127/452 (28%)
fdgt-1	NP_493982.1	MFS_GLUT_Class1	48..497	CDD:340989	129/478 (27%)