Protein Alignment CG10960 and SLC2A12

DIOPT Version :9

• Sequence 1: NP_648605.1
• Gene: CG10960 / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_660159.1
• Gene: SLC2A12 / 154091
• HGNCID: 18067
• Length: 617
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 141/565 - (24%)
• Similarity: 242/565 - (42%)
• Gaps: 115/565 - (20%)

  Fly    64 NLLGNMVHTSTSNNSQ-KWPQ------YVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFP 121
            |..|..|.|..|.:.. .|.:      :::::.||......|..||..|.|..:|...     ..
Human    14 NQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTL-----LA 73

  Fly   122 VDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRF 186
            :...:...|.|::.:||....:..|.||:..||:..::.......||..:||.:::.::|...|.
Human    74 LSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRI 138

  Fly   187 ILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYA-------VGAGVK-IFWLS 243
            .:|::.....:...:|..|||.:..||.|.|..:|||.||||..|.       |..|.| :|.|.
Human   139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLV 203

  Fly   244 IICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANK 308
            |..|:|..|   ..:|:|.||.:||.|.:...|.|.:..||... |...||..::.:.::  ..:
Human   204 IPLGVLQAI---AMYFLPPSPRFLVMKGQEGAASKVLGRLRALS-DTTEELTVIKSSLKD--EYQ 262

  Fly   309 VNVWAAL-NRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATIL----IGI 368
            .:.|... ::...|..:.|.:.|:||.|:.|...::||||.:.  .:.|.::..|..|    :|:
Human   263 YSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVL--KSVGFQSNEAASLASTGVGV 325

  Fly   369 MQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVY----------------FFLQKQDAA- 416
            ::|::|..:||:||.:|.:..|......||.|...:|:.                ...|..|.:
Human   326 VKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESV 390

  Fly   417 ---------------------------------------------------------QVVS---- 420
                                                                     |:|:
Human   391 IYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGD 455

  Fly   421 ----LGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVN 481
                |.||.:|||.:::..||||.||:|||::.|:|...|:|.|.:|..:.||.:..:::.||:.
Human   456 VPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLT 520

  Fly   482 LNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELA 526
            :.|.:|:....:::..:::..::||...:|||||.||.:|..|||
Human   521 VTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELA 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	110/451 (24%)
		MFS	118..508	CDD:119392	116/484 (24%)
SLC2A12	NP_660159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		5/14 (36%)
		Sugar_tr	44..561	CDD:306568	131/529 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750