Protein Alignment nebu and SLC2A14

DIOPT Version :10

• Sequence 1: NP_648605.1
• Gene: nebu / 39458
• FlyBaseID: FBgn0036316
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 148/512 - (28%)
• Similarity: 243/512 - (47%)
• Gaps: 62/512 - (12%)

  Fly    63 ENLLG-----NMVH------TSTSNNSQK-------WPQYVAALAAAG-GAFAAGTVLGWTSPAE 108
            |.|||     .|.|      |||...||.       .|..:.|:..|. |:|..|...|..:..|
Human    10 EVLLGVKQGDEMRHFFFSSQTSTLEKSQNGGVGEEVTPALIFAITVATIGSFQFGYNTGVINAPE 74

  Fly   109 T---EIVDR--GEGYDFPVDK----DQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLP 164
            |   |.:::  .:..:.|..:    :.:|...:..::|.......:|..:|..||:.:||.:.|.
Human    75 TIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLL 139

  Fly   165 FILGWTML---IWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIG 226
            ...|..::   ..|.:|.||...|.::|:..|......|||.|||:...:||..|:..||.|.||
Human   140 AATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIG 204

  Fly   227 ILFVYAVGAGVKIFWLSIICG------------ILPLIF-GAIFFFMPESPTY-LVSKDRSENAI 277
            ||.       .:||.|.:|.|            |||.|. .|.....||||.: |:::.:.|||.
Human   205 ILV-------AQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENAT 262

  Fly   278 KSIQWLRGKEYDYEPELAELR-ETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINA 341
            :.:|.|.|.: |...::.|:: |:.|.::..:|.|.........|:.:.||:.|...||:.||||
Human   263 RILQRLWGTQ-DVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINA 326

  Fly   342 VIFYASRIFLEANTGIEAE-WATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIG 405
            |.:|::.||.:|  |::.. :|||..|::..:.|.:|..:|::.|||.|.:.....||..:|.:.
Human   327 VFYYSTGIFKDA--GVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMT 389

  Fly   406 VYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWL 470
            |...|:.    ....:.::.:.::.:|:..|.||.||:||.::.|||:...:..|.::||.|||.
Human   390 VSLLLKN----HYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWT 450

  Fly   471 LAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAG 527
            ..|:|...|.:....|| ...|.:|.|..:..:.|.:|.||||:|::..:|.:...|
Human   451 SNFLVGLLFPSAAYYLG-AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEG 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nebu	NP_648605.1	MFS_GLUT6_8_Class3_like	99..520	CDD:340916	129/448 (29%)
SLC2A14	NP_001273166.1	MFS_GLUT_Class1	51..495	CDD:340989	133/458 (29%)