DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a11l2

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001339155.2	Gene:	slc2a11l2 / 110386950	-ID:	-	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	485	Identity:	122/485 - (25%)
Similarity:	210/485 - (43%)	Gaps:	73/485 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 YVAALAAAGGAFAAG---TVLGWTSPAETEIVDRGEGYDFPVDKDQFSWVG-------------- 131
            ::|.:...|..|..|   :||...||...:.::.             ||:.
Frog    16 FMAFIMGIGSTFQYGYQISVLNSPSPFIKQFINE-------------SWMRRHETTITQGTHTLI 67

  Fly   132 -----SAMTLGAACVCIPIGFLINMIGRKWTMLF-----LVLPFILGWTMLIWAVNVSMLYASRF 186
                 |..::|.....:..|:|...:|:|..||:     |:...::|.:..:..  ..::...||
Frog    68 WSLTVSVFSIGCLIGSVSSGYLSGKLGKKKCMLYNTFLPLINTVLMGLSQTVGL--FELIIVGRF 130

  Fly   187 ILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGA----GVKIFWLSII-- 245
            :.||..|........|.||.|.:::.|.|.....:.:|:|.|....||.    |.::.|..|:
Frog   131 LCGIYVGLGLNIHAQYIGESAPRKLLGFLNCLAPMFVTLGKLCGQIVGIRELFGTELMWPYILVP 195

  Fly   246 CGILPLIFGAIFFFMPESPTYLVS-KDRSENAIKSIQWLRGKEYDYEPELAELRETDR-ETKANK 308
            .||..|:........||:|.||:. |...|..:|:::.|.| :.|::.|:.|:.|..| :.|...
Frog   196 SGITSLVQLITLPLFPETPHYLLQVKGDKEACVKALKQLWG-DRDHQAEIEEMIEQQRAQKKTGN 259

  Fly   309 VNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEAN-TGIEAEWATILIGIMQVV 372
            :.:...|..|..|..|...:||:...|:.|.||:.||:..:|..|| ...:..:.:|.:|..:.|
Frog   260 MGILELLKDPSHRWQLYSMIGLILTMQLSGANAIYFYSYDVFRAANFPPDKISYVSIGVGAFEFV 324

  Fly   373 ATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCL-FIIMF 436
            :..|.:|:::..||:.|:|.....|::....:.|...||.       |..|:|..|:.| |..:|
Frog   325 SAMVCSLLIEHFGRKFLMLGGFSLMSLILGLLTVTLSLQD-------SYLWMPYCSVALVFSFIF 382

  Fly   437 SIGYGPVPWLMMGELFATDIKGFAG-------SLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWL 494
            ..|.||.     |.:|.|.::.||.       :::|..:|:..:::...|..|...|| ...|.|
Frog   383 VFGAGPA-----GSIFTTCVEIFAQAPRVPALAVSGVFSWVGLYILGMIFPYLVGTLG-HFCFLL 441

  Fly   495 FAGLTVVGVIFVYFAVPETKGKSLNEIQQE 524
            |..:.::.....:|.||||||||:.:|.||
Frog   442 FIAVMLISSTLAFFIVPETKGKSIAQISQE 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	95/397 (24%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	102/430 (24%)
slc2a11l2	NP_001339155.2	MFS	17..468	CDD:421695	119/479 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910