DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a4

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_031755513.1	Gene:	slc2a4 / 101731550	XenbaseID:	XB-GENE-5943313	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	499	Identity:	144/499 - (28%)
Similarity:	239/499 - (47%)	Gaps:	76/499 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSWV-----GSA----------- 133
            ::...|..|:|..|..:|..: |..:|::  :.|:       .||:     |||
Frog    26 LSVFTAILGSFQFGYNIGVIN-APQKIIE--QSYN-------ESWISRSSSGSASIDPGLLRTLW 80

  Fly   134 ------MTLGAACVCIPIGFLINMIGRKWTMLF-LVLPFILGWTMLIWAV--NVSMLYASRFILG 189
                  .::|.....:.:|.:...:|||..|:. .|..|:.|..|.:..|  :..|:...||::|
Frog    81 SLSVAIFSIGGMVSSLSVGVVSQWLGRKRAMVINNVFAFLAGSFMGLSQVCQSYEMMIVGRFLIG 145

  Fly   190 IAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGV---------KIFWLSII 245
            :..|......|||.|||:...:||.:|:..||.:.||||....:|..:         .:||:::|
Frog   146 VYSGLASGLVPMYVGEISPTHLRGAMGTLHQLSLVIGILVAQVLGLELFLGTNTRWPALFWVTLI 210

  Fly   246 -----CGILPLIFGAIFFFMPESPTYL-VSKDRSENAIKSIQWLRGKEYDYEPELAEL----RET 300
                 |.:||        |.||||.:| :..::...|.||::.|.|.. |...:|:::    |:.
Frog   211 PAALQCLMLP--------FCPESPRFLYIVCEQEAQAKKSLRRLTGLP-DVTDDLSDMKEEKRQM 266

  Fly   301 DRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAE-WATI 364
            |.|.|.:.:.::.:.|   .|:.:.:::.|...||:.||||:.:|::.||.:|  |:|.. :|||
Frog   267 DSEPKVSILQIFRSRN---YRQPILVAIVLQLSQQLSGINAIFYYSTDIFSKA--GVEQPIYATI 326

  Fly   365 LIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASL 429
            ..||:....|.||..:|::.|||.|.|.....|.:....:.....||:    .|.||.:|.:|::
Frog   327 GAGIVNTAFTVVSLFLVERAGRRTLQLLGLAGMIVCALLMTAAMVLQE----SVPSLSYLSMAAI 387

  Fly   430 CLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWL 494
            ..|:..|.||.||:||.::.|||:...:..|.::||.:||...|::...|..:.:..| ...|.|
Frog   388 FGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAIAGCTNWTSNFIIGMGFQYVAELCG-PYVFLL 451

  Fly   495 FAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAE 538
            |..|....:||.||.||||:|:|.:||..  |..|..|..:..|
Frog   452 FGALLFAFLIFTYFRVPETRGRSFDEISH--AFRRRNPSLLDHE 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	114/401 (28%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	123/434 (28%)
slc2a4	XP_031755513.1	MFS_GLUT_Class1	26..473	CDD:340989	136/475 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010